AMPK activation attenuates cancer-induced bone pain by reducing mitochondrial dysfunction-mediated neuroinflammation: AMPK activation attenuates bone cancer pain

Bone metastasis of cancer cells leads to severe pain by disrupting bone structure and inducing central sensitization. Neuroinflammation in the spinal cord plays a decisive role in the maintenance and development of pain. In the current study, male Sprague-Dawley (SD) rats are used to establish a can...

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Detalles Bibliográficos
Autores principales: Yang, Heyu, Wang, Yujia, Zhen, Shuqing, Wang, Banghua, Jiao, Ming, Liu, Ling, Li, Dai, Zhu, Haili, Xie, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10160234/
https://www.ncbi.nlm.nih.gov/pubmed/36971458
http://dx.doi.org/10.3724/abbs.2023039

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