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The magic of small-molecule drugs during ex vivo expansion in adoptive cell therapy

In the past decades, advances in the use of adoptive cellular therapy to treat cancer have led to unprecedented responses in patients with relapsed/refractory or late-stage malignancies. However, cellular exhaustion and senescence limit the efficacy of FDA-approved T-cell therapies in patients with...

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Detalles Bibliográficos
Autores principales:	Zhang, Hanwen, Passang, Tenzin, Ravindranathan, Sruthi, Bommireddy, Ramireddy, Jajja, Mohammad Raheel, Yang, Lily, Selvaraj, Periasamy, Paulos, Chrystal M., Waller, Edmund K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10160370/ https://www.ncbi.nlm.nih.gov/pubmed/37153607 http://dx.doi.org/10.3389/fimmu.2023.1154566

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