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Amlodipine rescues advanced iron overload cardiomyopathy in hemojuvelin knockout murine model: Clinical implications
BACKGROUND: Iron overload cardiomyopathy (IOC) is a major co-morbidity of genetic hemochromatosis and secondary iron overload with limited therapeutic options. We aim to investigate mechanisms of rescue action of amlodipine in the murine model of iron overload, characterize changes in human cardiac...
Autores principales: | Zhabyeyev, Pavel, Sadasivan, Chandu, Shah, Saumya, Wang, Faqi, Oudit, Gavin Y. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10160373/ https://www.ncbi.nlm.nih.gov/pubmed/37153462 http://dx.doi.org/10.3389/fcvm.2023.1129349 |
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