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Modulating sphingosine 1-phosphate receptor signaling skews intrahepatic leukocytes and attenuates murine nonalcoholic steatohepatitis

Sphingosine 1-phosphate (S1P) is a bioactive sphingolipid associated with nonalcoholic steatohepatitis (NASH). Immune cell-driven inflammation is a key determinant of NASH progression. Macrophages, monocytes, NK cells, T cells, NKT cells, and B cells variably express S1P receptors from a repertoire...

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Detalles Bibliográficos
Autores principales:	Liao, Chieh-Yu, Barrow, Fanta, Venkatesan, Nanditha, Nakao, Yasuhiko, Mauer, Amy S., Fredrickson, Gavin, Song, Myeong Jun, Sehrawat, Tejasav S., Dasgupta, Debanjali, Graham, Rondell P., Revelo, Xavier S., Malhi, Harmeet
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10160388/ https://www.ncbi.nlm.nih.gov/pubmed/37153573 http://dx.doi.org/10.3389/fimmu.2023.1130184

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