Cargando…

Late-stage MC38 tumours recapitulate features of human colorectal cancer – implications for appropriate timepoint selection in preclinical studies

Anti-tumour T cell responses play a crucial role in controlling the progression of colorectal cancer (CRC), making this disease a promising candidate for immunotherapy. However, responses to immune-targeted therapies are currently limited to subpopulations of patients and specific types of cancer. C...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shields, Nicholas J., Peyroux, Estelle M., Ferguson, Angela L., Steain, Megan, Neumann, Silke, Young, Sarah L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10160415/ https://www.ncbi.nlm.nih.gov/pubmed/37153625 http://dx.doi.org/10.3389/fimmu.2023.1152035

Ejemplares similares

Multiomics single timepoint measurements to predict severe COVID-19
por: Tegethoff, Sina A, et al.
Publicado: (2023)

An Improved Synthesis of N-(4-[(18)F]Fluorobenzoyl)-Interleukin-2 for the Preclinical PET Imaging of Tumour-Infiltrating T-cells in CT26 and MC38 Colon Cancer Models
por: Khanapur, Shivashankar, et al.
Publicado: (2021)

Neuropsychological predictors of conversion from mild cognitive impairment to dementia at different timepoints
por: Quaranta, Davide, et al.
Publicado: (2023)

Synthetic Phosphorylation of p38α Recapitulates Protein Kinase Activity
por: Chooi, K. Phin, et al.
Publicado: (2014)

Single-Timepoint Snapshot of Hemoglobin: Is it Enough to Reflect the Dynamicity of Coronary Atherosclerosis?
por: Yang, Seokhun, et al.
Publicado: (2022)

Changes to Astrocyte-associated Protein Expression at Different Timepoints of Cuprizone Treatment
por: Frankle, Lana, et al.
Publicado: (2023)

Key correlates of exclusive breastfeeding at three timepoints: Evidence from Ethiopia
por: Yigletu, Seblewongel, et al.
Publicado: (2022)

Modelling stromal compartments to recapitulate the ameloblastoma tumour microenvironment
por: Bakkalci, Deniz, et al.
Publicado: (2022)

Bioengineered 3D models of human pancreatic cancer recapitulate in vivo tumour biology
por: Osuna de la Peña, David, et al.
Publicado: (2021)

AGEs and sRAGE Variations at Different Timepoints in Patients with Chronic Kidney Disease
por: Molinari, Paolo, et al.
Publicado: (2021)

Multiomics single timepoint measurements to predict severe COVID-19 – Authors' reply
por: Garapati, Kishore, et al.
Publicado: (2023)

Leveraging the Clinical Timepoints in Lung Cancer Screening to Engage Individuals in Tobacco Treatment
por: Park, Elyse R, et al.
Publicado: (2022)

The developmental programme for genesis of the entire kidney is recapitulated in Wilms tumour
por: Fukuzawa, Ryuji, et al.
Publicado: (2017)

MC38 Tumors Induce Musculoskeletal Defects in Colorectal Cancer
por: Huot, Joshua R., et al.
Publicado: (2021)

Decellularized small intestine submucosa device for temporomandibular joint meniscus repair: Acute timepoint safety study
por: Chung, William L., et al.
Publicado: (2022)

Resource: A multi‐species multi‐timepoint transcriptome database and webpage for the pineal gland and retina
por: Chang, Eric, et al.
Publicado: (2020)

The earlier, the better: the effects of different administration timepoints of sorafenib in suppressing the carcinogenesis of VEGF in rats
por: Li, Nan, et al.
Publicado: (2017)

Randomized Controlled Trial of Two Timepoints for Introduction of Standardized Complementary Food in Preterm Infants
por: Haiden, Nadja, et al.
Publicado: (2022)

1-year mortality in lung cancer in France according to key timepoints of care pathways
por: Rivière, Axelle, et al.
Publicado: (2022)

LMAP-09 RECAPITULATING LASER INTERSTITIAL THERMAL THERAPY IN PRECLINICAL BRAIN TUMOR MODELS
por: Haskell-Mendoza, Aden, et al.
Publicado: (2023)

Recapitulation
Publicado: (1866)

Preclinical anti-tumour activity of HexaBody-CD38, a next-generation CD38 antibody with superior complement-dependent cytotoxic activity
por: Hiemstra, Ida H., et al.
Publicado: (2023)

Preclinical transgenic and patient‐derived xenograft models recapitulate the radiological features of human adamantinomatous craniopharyngioma
por: Boult, Jessica K. R., et al.
Publicado: (2017)

MPTP-Treated Zebrafish Recapitulate ‘Late-Stage’ Parkinson’s-like Cognitive Decline
por: Bashirzade, Alim A. O., et al.
Publicado: (2022)

Multi‐timepoint pattern analysis: Influence of personality and behavior on decoding context‐dependent brain connectivity dynamics
por: Ganesan, Saampras, et al.
Publicado: (2021)

Adapting the multilevel model for estimation of the reliable change index (RCI) with multiple timepoints and multiple sources of error
por: Morgan‐Lopez, Antonio Alexander, et al.
Publicado: (2022)

305 Leveraging multi-timepoint blood samples to characterize cancer-associated mutations in the blood over time
por: Mack, Taralynn, et al.
Publicado: (2023)

The experiences and attitudes of family caregivers of adults with intellectual and developmental disabilities at different timepoints in the COVID-19 pandemic
por: Tarzi, Gabriel, et al.
Publicado: (2023)

Modelling spatiotemporal dynamics of cerebral blood flow using multiple-timepoint arterial spin labelling MRI
por: Pinto, Joana, et al.
Publicado: (2023)

Native envelope-based immunogens derived from critical timepoints in the development of breadth elicit rapid neutralizing antibodies in rabbits
por: Malherbe, DC, et al.
Publicado: (2012)

Patient-Specific Retinal Organoids Recapitulate Disease Features of Late-Onset Retinitis Pigmentosa
por: Gao, Mei-Ling, et al.
Publicado: (2020)

Widespread sharing of pneumococcal strains in a rural African setting: proximate villages are more likely to share similar strains that are carried at multiple timepoints
por: Senghore, Madikay, et al.
Publicado: (2022)

Xenografts derived from patients with head and neck cancer recapitulate patient tumour properties
por: Makita, Haruna, et al.
Publicado: (2021)

Human Immunocompetent Model of Neuroendocrine Liver Metastases Recapitulates Patient-Specific Tumour Microenvironment
por: Doornebal, Ewald Jan, et al.
Publicado: (2022)

Evaluation of statistical illiteracy in Latin American clinicians and the piloting evaluation of a short course across multiple timepoints
por: Soto-Mota, Adrian, et al.
Publicado: (2022)

ImmunoPET Imaging Identifies the Optimal Timepoint for Combination Therapy in Xenograft Models of Triple-Negative Breast Cancer
por: Li, Ziqi, et al.
Publicado: (2023)

Combining dendritic cells and B cells for presentation of oxidised tumour antigens to CD8(+) T cells
por: Grant, Melanie L, et al.
Publicado: (2017)

Discharge of late preterm newborn: appropriated, controlled…namely safe
por: Coscia, A, et al.
Publicado: (2014)

An efficient method for mining cross-timepoint gene regulation sequential patterns from time course gene expression datasets
por: Cheng, Chun-Pei, et al.
Publicado: (2013)

Gene Co-Expression Network Analysis Provides Novel Insights into Myostatin Regulation at Three Different Mouse Developmental Timepoints
por: Yang, Xuerong, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_nr66gp27eqlajvo6bqkfss598l