Species origin of exogenous transcription factors affects the activation of endogenous pluripotency markers and signaling pathways of porcine induced pluripotent stem cells

The incomplete silencing of exogenous transcription factors (TFs) and the lack of endogenous counterpart activation hampers the application of porcine induced pluripotent stem cells (piPSCs). We used porcine, bovine and murine TFs to reprogram porcine fetal fibroblasts. Porcine TFs-derived piPSCs (p...

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Detalles Bibliográficos
Autores principales: Zhou, Meng, Zhang, Manling, Guo, Tianxu, Zhao, Lihua, Guo, Xiyun, Yin, Zhibao, Cheng, Linxin, Liu, Han, Zhao, Lixia, Li, Xihe, Li, Rongfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10160484/
https://www.ncbi.nlm.nih.gov/pubmed/37152293
http://dx.doi.org/10.3389/fcell.2023.1196273

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