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Dangers of including outcome at baseline as a covariate in latent change score models: Results from simulations and empirical re-analyses

Latent change score modeling is a type of structural equation modeling used for estimating change over time. Often change is regressed on the initial value of the outcome variable. However, similarly to other regression analyses, this procedure may be susceptible to regression to the mean. The prese...

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Detalles Bibliográficos
Autores principales: Sorjonen, Kimmo, Ingre, Michael, Nilsonne, Gustav, Melin, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10160499/
https://www.ncbi.nlm.nih.gov/pubmed/37153390
http://dx.doi.org/10.1016/j.heliyon.2023.e15746
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author Sorjonen, Kimmo
Ingre, Michael
Nilsonne, Gustav
Melin, Bo
author_facet Sorjonen, Kimmo
Ingre, Michael
Nilsonne, Gustav
Melin, Bo
author_sort Sorjonen, Kimmo
collection PubMed
description Latent change score modeling is a type of structural equation modeling used for estimating change over time. Often change is regressed on the initial value of the outcome variable. However, similarly to other regression analyses, this procedure may be susceptible to regression to the mean. The present study employed simulations as well as re-analyses of previously published data, claimed to indicate reciprocal promoting effects of vocabulary and matrix reasoning on each other's longitudinal development. Both in simulations and empirical re-analyses, when adjusting for initial value on the outcome, latent change score modeling tended to indicate an effect of a predictor on the change in an outcome even when no change had taken place. Furthermore, analyses tended to indicate a paradoxical effect on change both forward and backward in time. We conclude that results from latent change score modeling are susceptible to regression to the mean when adjusting for the initial value on the outcome. Researchers are recommended not to regress change on the initial value included in the calculation of the change score when employing latent change score modeling but, instead, to define this parameter as a covariance.
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spelling pubmed-101604992023-05-06 Dangers of including outcome at baseline as a covariate in latent change score models: Results from simulations and empirical re-analyses Sorjonen, Kimmo Ingre, Michael Nilsonne, Gustav Melin, Bo Heliyon Research Article Latent change score modeling is a type of structural equation modeling used for estimating change over time. Often change is regressed on the initial value of the outcome variable. However, similarly to other regression analyses, this procedure may be susceptible to regression to the mean. The present study employed simulations as well as re-analyses of previously published data, claimed to indicate reciprocal promoting effects of vocabulary and matrix reasoning on each other's longitudinal development. Both in simulations and empirical re-analyses, when adjusting for initial value on the outcome, latent change score modeling tended to indicate an effect of a predictor on the change in an outcome even when no change had taken place. Furthermore, analyses tended to indicate a paradoxical effect on change both forward and backward in time. We conclude that results from latent change score modeling are susceptible to regression to the mean when adjusting for the initial value on the outcome. Researchers are recommended not to regress change on the initial value included in the calculation of the change score when employing latent change score modeling but, instead, to define this parameter as a covariance. Elsevier 2023-04-24 /pmc/articles/PMC10160499/ /pubmed/37153390 http://dx.doi.org/10.1016/j.heliyon.2023.e15746 Text en © 2023 The Authors https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Research Article
Sorjonen, Kimmo
Ingre, Michael
Nilsonne, Gustav
Melin, Bo
Dangers of including outcome at baseline as a covariate in latent change score models: Results from simulations and empirical re-analyses
title Dangers of including outcome at baseline as a covariate in latent change score models: Results from simulations and empirical re-analyses
title_full Dangers of including outcome at baseline as a covariate in latent change score models: Results from simulations and empirical re-analyses
title_fullStr Dangers of including outcome at baseline as a covariate in latent change score models: Results from simulations and empirical re-analyses
title_full_unstemmed Dangers of including outcome at baseline as a covariate in latent change score models: Results from simulations and empirical re-analyses
title_short Dangers of including outcome at baseline as a covariate in latent change score models: Results from simulations and empirical re-analyses
title_sort dangers of including outcome at baseline as a covariate in latent change score models: results from simulations and empirical re-analyses
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10160499/
https://www.ncbi.nlm.nih.gov/pubmed/37153390
http://dx.doi.org/10.1016/j.heliyon.2023.e15746
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