Hypoxia-induced Wnt/β-catenin signaling activation in subchondral bone osteoblasts leads to an osteoarthritis-like phenotype of chondrocytes in articular cartilage

Background: Osteoarthritis (OA) is a whole-joint disease and characterized by alterations in the articular cartilage, subchondral bone, ligaments, and synovial membrane. The crosstalk between cartilage and subchondral bone plays a crucial role in the pathogenesis and progression of OA. Hypoxia has b...

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Detalles Bibliográficos
Autores principales: Li, Fang, Tan, Qizhao, Li, Feng, Zhang, Ke, Liu, Zhongjun, Tian, Yun, Zhu, Tengjiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10160672/
https://www.ncbi.nlm.nih.gov/pubmed/37152900
http://dx.doi.org/10.3389/fmolb.2023.1057154

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10160672/
https://www.ncbi.nlm.nih.gov/pubmed/37152900
http://dx.doi.org/10.3389/fmolb.2023.1057154

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