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The Emergence of Mpox: Epidemiology and Current Therapeutic Options
The world recently witnessed the emergence of new epidemic outbreaks like COVID-19 and mpox. The 2022 outbreak of mpox amid COVID-19 presents an intricate situation and requires strategies to combat the status quo. Some of the challenges to controlling an epidemic include present knowledge of the di...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10160711/ https://www.ncbi.nlm.nih.gov/pubmed/37213566 http://dx.doi.org/10.1007/s40495-023-00318-y |
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author | Ranjan, Samriddhi Vashishth, Kanupriya Sak, Katrin Tuli, Hardeep Singh |
author_facet | Ranjan, Samriddhi Vashishth, Kanupriya Sak, Katrin Tuli, Hardeep Singh |
author_sort | Ranjan, Samriddhi |
collection | PubMed |
description | The world recently witnessed the emergence of new epidemic outbreaks like COVID-19 and mpox. The 2022 outbreak of mpox amid COVID-19 presents an intricate situation and requires strategies to combat the status quo. Some of the challenges to controlling an epidemic include present knowledge of the disease, available treatment options, appropriate health infrastructures facilities, current scientific methods, operations concepts, availability of technical staff, financial funds, and lastly international policies to control an epidemic state. These insufficiencies often hinder the control of disease spread and jeopardize the health of countless people. Also, disease outbreaks often put a huge burden on the developing economies. These countries are the worst affected and are immensely dependent on assistance provided from the larger economies to control such outbreaks. The first case of mpox was reported in the 1970s and several outbreaks were detected thereafter in the endemic areas eventually leading to the recent outbreak. Approximately, more than 80,000 individuals were infected, and 110 countries were affected by this outbreak. Yet, no definite vaccines and drugs are available to date. The lack of human clinical trials affected thousands of individuals in availing definite disease management. This paper focuses on the epidemiology of mpox, scientific concepts, and treatment options including future treatment modalities for mpox. |
format | Online Article Text |
id | pubmed-10160711 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Springer International Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-101607112023-05-09 The Emergence of Mpox: Epidemiology and Current Therapeutic Options Ranjan, Samriddhi Vashishth, Kanupriya Sak, Katrin Tuli, Hardeep Singh Curr Pharmacol Rep Article The world recently witnessed the emergence of new epidemic outbreaks like COVID-19 and mpox. The 2022 outbreak of mpox amid COVID-19 presents an intricate situation and requires strategies to combat the status quo. Some of the challenges to controlling an epidemic include present knowledge of the disease, available treatment options, appropriate health infrastructures facilities, current scientific methods, operations concepts, availability of technical staff, financial funds, and lastly international policies to control an epidemic state. These insufficiencies often hinder the control of disease spread and jeopardize the health of countless people. Also, disease outbreaks often put a huge burden on the developing economies. These countries are the worst affected and are immensely dependent on assistance provided from the larger economies to control such outbreaks. The first case of mpox was reported in the 1970s and several outbreaks were detected thereafter in the endemic areas eventually leading to the recent outbreak. Approximately, more than 80,000 individuals were infected, and 110 countries were affected by this outbreak. Yet, no definite vaccines and drugs are available to date. The lack of human clinical trials affected thousands of individuals in availing definite disease management. This paper focuses on the epidemiology of mpox, scientific concepts, and treatment options including future treatment modalities for mpox. Springer International Publishing 2023-05-05 2023 /pmc/articles/PMC10160711/ /pubmed/37213566 http://dx.doi.org/10.1007/s40495-023-00318-y Text en © The Author(s), under exclusive licence to Springer Nature Switzerland AG 2023, Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
spellingShingle | Article Ranjan, Samriddhi Vashishth, Kanupriya Sak, Katrin Tuli, Hardeep Singh The Emergence of Mpox: Epidemiology and Current Therapeutic Options |
title | The Emergence of Mpox: Epidemiology and Current Therapeutic Options |
title_full | The Emergence of Mpox: Epidemiology and Current Therapeutic Options |
title_fullStr | The Emergence of Mpox: Epidemiology and Current Therapeutic Options |
title_full_unstemmed | The Emergence of Mpox: Epidemiology and Current Therapeutic Options |
title_short | The Emergence of Mpox: Epidemiology and Current Therapeutic Options |
title_sort | emergence of mpox: epidemiology and current therapeutic options |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10160711/ https://www.ncbi.nlm.nih.gov/pubmed/37213566 http://dx.doi.org/10.1007/s40495-023-00318-y |
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