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The Emergence of Mpox: Epidemiology and Current Therapeutic Options

The world recently witnessed the emergence of new epidemic outbreaks like COVID-19 and mpox. The 2022 outbreak of mpox amid COVID-19 presents an intricate situation and requires strategies to combat the status quo. Some of the challenges to controlling an epidemic include present knowledge of the di...

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Autores principales: Ranjan, Samriddhi, Vashishth, Kanupriya, Sak, Katrin, Tuli, Hardeep Singh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10160711/
https://www.ncbi.nlm.nih.gov/pubmed/37213566
http://dx.doi.org/10.1007/s40495-023-00318-y
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author Ranjan, Samriddhi
Vashishth, Kanupriya
Sak, Katrin
Tuli, Hardeep Singh
author_facet Ranjan, Samriddhi
Vashishth, Kanupriya
Sak, Katrin
Tuli, Hardeep Singh
author_sort Ranjan, Samriddhi
collection PubMed
description The world recently witnessed the emergence of new epidemic outbreaks like COVID-19 and mpox. The 2022 outbreak of mpox amid COVID-19 presents an intricate situation and requires strategies to combat the status quo. Some of the challenges to controlling an epidemic include present knowledge of the disease, available treatment options, appropriate health infrastructures facilities, current scientific methods, operations concepts, availability of technical staff, financial funds, and lastly international policies to control an epidemic state. These insufficiencies often hinder the control of disease spread and jeopardize the health of countless people. Also, disease outbreaks often put a huge burden on the developing economies. These countries are the worst affected and are immensely dependent on assistance provided from the larger economies to control such outbreaks. The first case of mpox was reported in the 1970s and several outbreaks were detected thereafter in the endemic areas eventually leading to the recent outbreak. Approximately, more than 80,000 individuals were infected, and 110 countries were affected by this outbreak. Yet, no definite vaccines and drugs are available to date. The lack of human clinical trials affected thousands of individuals in availing definite disease management. This paper focuses on the epidemiology of mpox, scientific concepts, and treatment options including future treatment modalities for mpox.
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spelling pubmed-101607112023-05-09 The Emergence of Mpox: Epidemiology and Current Therapeutic Options Ranjan, Samriddhi Vashishth, Kanupriya Sak, Katrin Tuli, Hardeep Singh Curr Pharmacol Rep Article The world recently witnessed the emergence of new epidemic outbreaks like COVID-19 and mpox. The 2022 outbreak of mpox amid COVID-19 presents an intricate situation and requires strategies to combat the status quo. Some of the challenges to controlling an epidemic include present knowledge of the disease, available treatment options, appropriate health infrastructures facilities, current scientific methods, operations concepts, availability of technical staff, financial funds, and lastly international policies to control an epidemic state. These insufficiencies often hinder the control of disease spread and jeopardize the health of countless people. Also, disease outbreaks often put a huge burden on the developing economies. These countries are the worst affected and are immensely dependent on assistance provided from the larger economies to control such outbreaks. The first case of mpox was reported in the 1970s and several outbreaks were detected thereafter in the endemic areas eventually leading to the recent outbreak. Approximately, more than 80,000 individuals were infected, and 110 countries were affected by this outbreak. Yet, no definite vaccines and drugs are available to date. The lack of human clinical trials affected thousands of individuals in availing definite disease management. This paper focuses on the epidemiology of mpox, scientific concepts, and treatment options including future treatment modalities for mpox. Springer International Publishing 2023-05-05 2023 /pmc/articles/PMC10160711/ /pubmed/37213566 http://dx.doi.org/10.1007/s40495-023-00318-y Text en © The Author(s), under exclusive licence to Springer Nature Switzerland AG 2023, Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Article
Ranjan, Samriddhi
Vashishth, Kanupriya
Sak, Katrin
Tuli, Hardeep Singh
The Emergence of Mpox: Epidemiology and Current Therapeutic Options
title The Emergence of Mpox: Epidemiology and Current Therapeutic Options
title_full The Emergence of Mpox: Epidemiology and Current Therapeutic Options
title_fullStr The Emergence of Mpox: Epidemiology and Current Therapeutic Options
title_full_unstemmed The Emergence of Mpox: Epidemiology and Current Therapeutic Options
title_short The Emergence of Mpox: Epidemiology and Current Therapeutic Options
title_sort emergence of mpox: epidemiology and current therapeutic options
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10160711/
https://www.ncbi.nlm.nih.gov/pubmed/37213566
http://dx.doi.org/10.1007/s40495-023-00318-y
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