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Impact of the COVID-19 Pandemic on Tuberculosis Testing and Treatment at a Tertiary Hospital in Zambia

Globally, tuberculosis (TB) testing and treatment have declined dramatically during the COVID-19 pandemic. We quantified the change in TB visits, testing, and treatment compared with a 12-month pre-pandemic baseline at the national referral hospital’s TB Clinic in Lusaka, Zambia, in the first year o...

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Autores principales: Rosser, Joelle I., Phiri, Christabel, Bramante, Juliette T., Fwoloshi, Sombo, Kankasa, Chipepo, Lungu, Patrick, Chanda, Raphael, Chipimo, Peter, Mulenga, Lloyd, Claassen, Cassidy W., Chanda, Duncan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Tropical Medicine and Hygiene 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10160887/
https://www.ncbi.nlm.nih.gov/pubmed/36913923
http://dx.doi.org/10.4269/ajtmh.22-0689
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author Rosser, Joelle I.
Phiri, Christabel
Bramante, Juliette T.
Fwoloshi, Sombo
Kankasa, Chipepo
Lungu, Patrick
Chanda, Raphael
Chipimo, Peter
Mulenga, Lloyd
Claassen, Cassidy W.
Chanda, Duncan
author_facet Rosser, Joelle I.
Phiri, Christabel
Bramante, Juliette T.
Fwoloshi, Sombo
Kankasa, Chipepo
Lungu, Patrick
Chanda, Raphael
Chipimo, Peter
Mulenga, Lloyd
Claassen, Cassidy W.
Chanda, Duncan
author_sort Rosser, Joelle I.
collection PubMed
description Globally, tuberculosis (TB) testing and treatment have declined dramatically during the COVID-19 pandemic. We quantified the change in TB visits, testing, and treatment compared with a 12-month pre-pandemic baseline at the national referral hospital’s TB Clinic in Lusaka, Zambia, in the first year of the pandemic. We stratified the results into early and later pandemic periods. In the first 2 months of the pandemic, the mean number of monthly TB clinic visits, prescriptions, and positive TB polymerase chain reaction (PCR) tests decreased as follow: −94.1% (95% CI: −119.4 to −68.8%), −71.4% (95% CI: −80.4 to −62.4%), and −73% (95% CI: −95.5 to −51.3%), respectively. TB testing and treatment counts rebounded in the subsequent 10 months, although the number of prescriptions and TB-PCR tests performed remained significantly lower than pre-pandemic. The COVID-19 pandemic significantly disrupted TB care in Zambia, which could have long-lasting impacts on TB transmission and mortality. Future pandemic preparedness planning should incorporate strategies developed over the course of this pandemic to safeguard consistent, comprehensive TB care.
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spelling pubmed-101608872023-05-06 Impact of the COVID-19 Pandemic on Tuberculosis Testing and Treatment at a Tertiary Hospital in Zambia Rosser, Joelle I. Phiri, Christabel Bramante, Juliette T. Fwoloshi, Sombo Kankasa, Chipepo Lungu, Patrick Chanda, Raphael Chipimo, Peter Mulenga, Lloyd Claassen, Cassidy W. Chanda, Duncan Am J Trop Med Hyg Short Report Globally, tuberculosis (TB) testing and treatment have declined dramatically during the COVID-19 pandemic. We quantified the change in TB visits, testing, and treatment compared with a 12-month pre-pandemic baseline at the national referral hospital’s TB Clinic in Lusaka, Zambia, in the first year of the pandemic. We stratified the results into early and later pandemic periods. In the first 2 months of the pandemic, the mean number of monthly TB clinic visits, prescriptions, and positive TB polymerase chain reaction (PCR) tests decreased as follow: −94.1% (95% CI: −119.4 to −68.8%), −71.4% (95% CI: −80.4 to −62.4%), and −73% (95% CI: −95.5 to −51.3%), respectively. TB testing and treatment counts rebounded in the subsequent 10 months, although the number of prescriptions and TB-PCR tests performed remained significantly lower than pre-pandemic. The COVID-19 pandemic significantly disrupted TB care in Zambia, which could have long-lasting impacts on TB transmission and mortality. Future pandemic preparedness planning should incorporate strategies developed over the course of this pandemic to safeguard consistent, comprehensive TB care. The American Society of Tropical Medicine and Hygiene 2023-03-13 2023-05 /pmc/articles/PMC10160887/ /pubmed/36913923 http://dx.doi.org/10.4269/ajtmh.22-0689 Text en © The author(s) https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution (CC-BY) License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Short Report
Rosser, Joelle I.
Phiri, Christabel
Bramante, Juliette T.
Fwoloshi, Sombo
Kankasa, Chipepo
Lungu, Patrick
Chanda, Raphael
Chipimo, Peter
Mulenga, Lloyd
Claassen, Cassidy W.
Chanda, Duncan
Impact of the COVID-19 Pandemic on Tuberculosis Testing and Treatment at a Tertiary Hospital in Zambia
title Impact of the COVID-19 Pandemic on Tuberculosis Testing and Treatment at a Tertiary Hospital in Zambia
title_full Impact of the COVID-19 Pandemic on Tuberculosis Testing and Treatment at a Tertiary Hospital in Zambia
title_fullStr Impact of the COVID-19 Pandemic on Tuberculosis Testing and Treatment at a Tertiary Hospital in Zambia
title_full_unstemmed Impact of the COVID-19 Pandemic on Tuberculosis Testing and Treatment at a Tertiary Hospital in Zambia
title_short Impact of the COVID-19 Pandemic on Tuberculosis Testing and Treatment at a Tertiary Hospital in Zambia
title_sort impact of the covid-19 pandemic on tuberculosis testing and treatment at a tertiary hospital in zambia
topic Short Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10160887/
https://www.ncbi.nlm.nih.gov/pubmed/36913923
http://dx.doi.org/10.4269/ajtmh.22-0689
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