Cargando…

Challenges and shortcomings of antibacterial discovery projects

OBJECTIVES: Antibacterial drug discovery activities are essential for filling clinical pipelines with promising clinical candidates. Little information is available about the challenges and shortcomings of small companies and academic institutions in performing these important discovery tasks. METHO...

Descripción completa

Detalles Bibliográficos
Autores principales:	Theuretzbacher, Ursula, Baraldi, Enrico, Ciabuschi, Francesco, Callegari, Simone
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10160915/ https://www.ncbi.nlm.nih.gov/pubmed/36503116 http://dx.doi.org/10.1016/j.cmi.2022.11.027

Ejemplares similares

Insights into early stage of antibiotic development in small- and medium-sized enterprises: a survey of targets, costs, and durations
por: Årdal, Christine, et al.
Publicado: (2018)

Shortcomings in risk projection.
por: Harley, N H
Publicado: (1989)

The global preclinical antibacterial pipeline
por: Theuretzbacher, Ursula, et al.
Publicado: (2019)

Professional Shortcomings
por: Foster, J. H.
Publicado: (1871)

Municipal Shortcomings
Publicado: (1904)

Peptides as Pharmacological Carriers to the Brain: Promises, Shortcomings and Challenges
por: Parrasia, Sofia, et al.
Publicado: (2022)

Glioma surveillance imaging: current strategies, shortcomings, challenges and outlook
por: Abdalla, Gehad, et al.
Publicado: (2020)

The Shortcomings of Plenum Ventilation
Publicado: (1906)

The Publicness of Pandemic Security and the Shortcomings of Governmentality
por: Langenohl, Andreas
Publicado: (2022)

Cancer epidemiology: shortcomings and possibilities.
por: Clemmesen, J
Publicado: (1983)

The Hormesis Concept: Strengths and Shortcomings
por: Bondy, Stephen C.
Publicado: (2023)

Shortcomings in Dealing with Psychological Effects of Natural Disasters in Iran
por: RABIEI, Ali, et al.
Publicado: (2014)

Shortcomings in addressing attacks on health care
por: Jaff, Dilshad
Publicado: (2018)

The current status and shortcomings of stereotactic radiosurgery
por: Mehrens, Hunter, et al.
Publicado: (2022)

Evolution, Benefits, and Shortcomings of Vaccine Management
por: McCullers, Jonathan A.
Publicado: (2007)

Methodological Shortcomings of Wrist-Worn Heart Rate Monitors Validations
por: Sartor, Francesco, et al.
Publicado: (2018)

Using Nuclear Energy for Maritime Decarbonization and Related Environmental Challenges: Existing Regulatory Shortcomings and Improvements
por: Wang, Qiuwen, et al.
Publicado: (2023)

Hemicrania continua: major shortcomings in the new classification
por: Fredriksen, Torbjørn A, et al.
Publicado: (2014)

Immunotherapy in Glioblastoma: Current Shortcomings and Future Perspectives
por: Weenink, Bas, et al.
Publicado: (2020)

The I. H. A. and Its Supposed Shortcomings
por: Berridge, E. W.
Publicado: (1884)

Human inference: strategies and shortcomings of social judgment
por: Nisbett, Richard, et al.
Publicado: (1980)

Evaluating the Performance of ChatGPT in Ophthalmology: An Analysis of Its Successes and Shortcomings
por: Antaki, Fares, et al.
Publicado: (2023)

Serious Shortcomings in the Management of Children with Anaphylaxis in Scottish Schools
por: Rankin, Kirsty E, et al.
Publicado: (2006)

Antibacterial Discovery: 21st Century Challenges
por: Hoffman, Paul S.
Publicado: (2020)

The shortcomings of identity: Champeta, culture, and inequality in Cartagena, Colombia
por: Cabarcas Ortega, Marcelo José
Publicado: (2023)

Shortcomings of SARS-CoV-2 genomic metadata
por: Gozashti, Landen, et al.
Publicado: (2021)

Sugarcane Ratooning Ability: Research Status, Shortcomings, and Prospects
por: Xu, Fu, et al.
Publicado: (2021)

Shortcomings in Pharmacy Benefit Forecasting - Interferon Beta Products
por: Rich, Sheldon
Publicado: (2003)

Outpatient pulmonary rehabilitation – rehabilitation models and shortcomings in outpatient aftercare
por: Korczak, Dieter, et al.
Publicado: (2010)

Shortcomings of Vitamin D-Based Model Simulations of Seasonal Influenza
por: Shaman, Jeffrey, et al.
Publicado: (2011)

Early childhood caries trends and surveillance shortcomings in the Czech Republic
por: Lenčová, Erika, et al.
Publicado: (2012)

The potential and shortcomings of mitochondrial DNA analysis for cheetah conservation management
por: Meißner, René, et al.
Publicado: (2022)

Linking Sustainable Use Policies to Novel Economic Incentives to Stimulate Antibiotic Research and Development
por: Theuretzbacher, Ursula, et al.
Publicado: (2017)

The Shortcomings of Radiologic Staging for Rectal Cancer and the Impact on the Treatment Plan
por: Alsanea, Nasser
Publicado: (2013)

Impacts and shortcomings of genetic clustering methods for infectious disease outbreaks
por: Poon, Art F. Y.
Publicado: (2016)

Public Psychological Health in COVID-19 Outbreak: Actions and Shortcomings
por: Jaberi, Azita
Publicado: (2020)

Applications of Raman Spectroscopy in Bacterial Infections: Principles, Advantages, and Shortcomings
por: Wang, Liang, et al.
Publicado: (2021)

Non-Standardized Terminology in Healthcare: Shortcomings and Subsequent Rectifications [Letter]
por: Kumar, Harit, et al.
Publicado: (2022)

CAR T Cell Therapy for Chronic Lymphocytic Leukemia: Successes and Shortcomings
por: Todorovic, Zeljko, et al.
Publicado: (2022)

Diagnosis of poor safety culture as a major shortcoming in OHSAS 18001-certified companies
por: GHAHRAMANI, Abolfazl
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_cb8d2i7il2rj5nifblpgmoefb8