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Alisertib exerts KRAS allele‑specific anticancer effects on colorectal cancer cell lines

The aim of the present study was to examine the effects of alisertib (ALS) on RAS signaling pathways against a panel of colorectal cancer (CRC) cell lines and engineered Flp-In stable cell lines expressing different Kirsten rat sarcoma virus (KRAS) mutants. The viability of Caco-2(KRAS wild-type), C...

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Detalles Bibliográficos
Autores principales:	Ren, Baojun, Geng, Yan, Chen, Shuxiang, Gao, Zhuowei, Zheng, Kehong, Yang, Yong, Luo, Qimei, Feng, Jing, Luo, Zhentao, Ju, Yongle, Huang, Zonghai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2023
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10160916/ https://www.ncbi.nlm.nih.gov/pubmed/37153900 http://dx.doi.org/10.3892/etm.2023.11942

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