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Film measurement and analytical approach for assessing treatment accuracy and latency in a magnetic resonance‐guided radiotherapy system

PURPOSE: We measure the dose distribution of gated delivery for different target motions and estimate the gating latency in a magnetic resonance‐guided radiotherapy (MRgRT) system. METHOD: The dose distribution accuracy of the gated MRgRT system (MRIdian, Viewray) was investigated using an in‐house‐...

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Autores principales: Nakayama, Hiroki, Okamoto, Hiroyuki, Nakamura, Satoshi, Iijima, Kotaro, Chiba, Takahito, Takemori, Mihiro, Nakaichi, Tetsu, Mikasa, Shohei, Fujii, Kyohei, Sakasai, Tatsuya, Kuwahara, Junichi, Miura, Yuki, Fujiyama, Daisuke, Tsunoda, Yuki, Hanzawa, Takuma, Igaki, Hiroshi, Chang, Weishan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10161048/
https://www.ncbi.nlm.nih.gov/pubmed/36934441
http://dx.doi.org/10.1002/acm2.13915
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author Nakayama, Hiroki
Okamoto, Hiroyuki
Nakamura, Satoshi
Iijima, Kotaro
Chiba, Takahito
Takemori, Mihiro
Nakaichi, Tetsu
Mikasa, Shohei
Fujii, Kyohei
Sakasai, Tatsuya
Kuwahara, Junichi
Miura, Yuki
Fujiyama, Daisuke
Tsunoda, Yuki
Hanzawa, Takuma
Igaki, Hiroshi
Chang, Weishan
author_facet Nakayama, Hiroki
Okamoto, Hiroyuki
Nakamura, Satoshi
Iijima, Kotaro
Chiba, Takahito
Takemori, Mihiro
Nakaichi, Tetsu
Mikasa, Shohei
Fujii, Kyohei
Sakasai, Tatsuya
Kuwahara, Junichi
Miura, Yuki
Fujiyama, Daisuke
Tsunoda, Yuki
Hanzawa, Takuma
Igaki, Hiroshi
Chang, Weishan
author_sort Nakayama, Hiroki
collection PubMed
description PURPOSE: We measure the dose distribution of gated delivery for different target motions and estimate the gating latency in a magnetic resonance‐guided radiotherapy (MRgRT) system. METHOD: The dose distribution accuracy of the gated MRgRT system (MRIdian, Viewray) was investigated using an in‐house‐developed phantom that was compatible with the magnetic field and gating method. This phantom contains a simulated tumor and a radiochromic film (EBT3, Ashland, Inc.). To investigate the effect of the number of beam switching and target velocity on the dose distribution, two types of target motions were applied. One is that the target was periodically moved at a constant velocity of 5 mm/s with different pause times (0, 1, 3, 10, and 20 s) between the motions. During different pause times, different numbers of beams were switched on/off. The other one is that the target was moved at velocities of 3, 5, 8, and 10 mm/s without any pause (i.e., continuous motion). The gated method was applied to these motions at MRIdian, and the dose distributions in each condition were measured using films. To investigate the relation between target motion and dose distribution in the gating method, we compared the results of the gamma analysis of the calculated and measured dose distributions. Moreover, we analytically estimated the gating latencies from the dose distributions measured using films and the gamma analysis results. RESULTS: The gamma pass rate linearly decreased with increasing beam switching and target velocity. The overall gating latencies of beam‐hold and beam‐on were 0.51 ± 0.17 and 0.35 ± 0.05 s, respectively. CONCLUSIONS: Film measurements highlighted the factors affecting the treatment accuracy of the gated MRgRT system. Our analytical approach, employing gamma analysis on films, can be used to estimate the overall latency of the gated MRgRT system.
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spelling pubmed-101610482023-05-06 Film measurement and analytical approach for assessing treatment accuracy and latency in a magnetic resonance‐guided radiotherapy system Nakayama, Hiroki Okamoto, Hiroyuki Nakamura, Satoshi Iijima, Kotaro Chiba, Takahito Takemori, Mihiro Nakaichi, Tetsu Mikasa, Shohei Fujii, Kyohei Sakasai, Tatsuya Kuwahara, Junichi Miura, Yuki Fujiyama, Daisuke Tsunoda, Yuki Hanzawa, Takuma Igaki, Hiroshi Chang, Weishan J Appl Clin Med Phys Radiation Measurements PURPOSE: We measure the dose distribution of gated delivery for different target motions and estimate the gating latency in a magnetic resonance‐guided radiotherapy (MRgRT) system. METHOD: The dose distribution accuracy of the gated MRgRT system (MRIdian, Viewray) was investigated using an in‐house‐developed phantom that was compatible with the magnetic field and gating method. This phantom contains a simulated tumor and a radiochromic film (EBT3, Ashland, Inc.). To investigate the effect of the number of beam switching and target velocity on the dose distribution, two types of target motions were applied. One is that the target was periodically moved at a constant velocity of 5 mm/s with different pause times (0, 1, 3, 10, and 20 s) between the motions. During different pause times, different numbers of beams were switched on/off. The other one is that the target was moved at velocities of 3, 5, 8, and 10 mm/s without any pause (i.e., continuous motion). The gated method was applied to these motions at MRIdian, and the dose distributions in each condition were measured using films. To investigate the relation between target motion and dose distribution in the gating method, we compared the results of the gamma analysis of the calculated and measured dose distributions. Moreover, we analytically estimated the gating latencies from the dose distributions measured using films and the gamma analysis results. RESULTS: The gamma pass rate linearly decreased with increasing beam switching and target velocity. The overall gating latencies of beam‐hold and beam‐on were 0.51 ± 0.17 and 0.35 ± 0.05 s, respectively. CONCLUSIONS: Film measurements highlighted the factors affecting the treatment accuracy of the gated MRgRT system. Our analytical approach, employing gamma analysis on films, can be used to estimate the overall latency of the gated MRgRT system. John Wiley and Sons Inc. 2023-03-19 /pmc/articles/PMC10161048/ /pubmed/36934441 http://dx.doi.org/10.1002/acm2.13915 Text en © 2023 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, LLC on behalf of The American Association of Physicists in Medicine. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Measurements
Nakayama, Hiroki
Okamoto, Hiroyuki
Nakamura, Satoshi
Iijima, Kotaro
Chiba, Takahito
Takemori, Mihiro
Nakaichi, Tetsu
Mikasa, Shohei
Fujii, Kyohei
Sakasai, Tatsuya
Kuwahara, Junichi
Miura, Yuki
Fujiyama, Daisuke
Tsunoda, Yuki
Hanzawa, Takuma
Igaki, Hiroshi
Chang, Weishan
Film measurement and analytical approach for assessing treatment accuracy and latency in a magnetic resonance‐guided radiotherapy system
title Film measurement and analytical approach for assessing treatment accuracy and latency in a magnetic resonance‐guided radiotherapy system
title_full Film measurement and analytical approach for assessing treatment accuracy and latency in a magnetic resonance‐guided radiotherapy system
title_fullStr Film measurement and analytical approach for assessing treatment accuracy and latency in a magnetic resonance‐guided radiotherapy system
title_full_unstemmed Film measurement and analytical approach for assessing treatment accuracy and latency in a magnetic resonance‐guided radiotherapy system
title_short Film measurement and analytical approach for assessing treatment accuracy and latency in a magnetic resonance‐guided radiotherapy system
title_sort film measurement and analytical approach for assessing treatment accuracy and latency in a magnetic resonance‐guided radiotherapy system
topic Radiation Measurements
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10161048/
https://www.ncbi.nlm.nih.gov/pubmed/36934441
http://dx.doi.org/10.1002/acm2.13915
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