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Programmed cell death-1 receptor-mediated regulation of Tbet(+)NK1.1(−) innate lymphoid cells within the tumor microenvironment

Innate lymphoid cells (ILCs) play a key role in tissue-mediated immunity and can be controlled by coreceptor signaling. Here, we define a subset of ILCs that are Tbet(+)NK1.1(−) and are present within the tumor microenvironment (TME). We show programmed death-1 receptor (PD-1) expression on ILCs wit...

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Detalles Bibliográficos
Autores principales: Lim, Jing Xuan, Lai, Chester Y., Mallett, Grace E., McDonald, David, Hulme, Gillian, Laba, Stephanie, Shapanis, Andrew, Payne, Megan, Patterson, Warren, Alexander, Michael, Coxhead, Jonathan, Filby, Andrew, Plummer, Ruth, Lovat, Penny E., Sciume, Giuseppe, Healy, Eugene, Amarnath, Shoba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10161089/
https://www.ncbi.nlm.nih.gov/pubmed/37098069
http://dx.doi.org/10.1073/pnas.2216587120