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Programmed cell death-1 receptor-mediated regulation of Tbet(+)NK1.1(−) innate lymphoid cells within the tumor microenvironment
Innate lymphoid cells (ILCs) play a key role in tissue-mediated immunity and can be controlled by coreceptor signaling. Here, we define a subset of ILCs that are Tbet(+)NK1.1(−) and are present within the tumor microenvironment (TME). We show programmed death-1 receptor (PD-1) expression on ILCs wit...
Autores principales: | Lim, Jing Xuan, Lai, Chester Y., Mallett, Grace E., McDonald, David, Hulme, Gillian, Laba, Stephanie, Shapanis, Andrew, Payne, Megan, Patterson, Warren, Alexander, Michael, Coxhead, Jonathan, Filby, Andrew, Plummer, Ruth, Lovat, Penny E., Sciume, Giuseppe, Healy, Eugene, Amarnath, Shoba |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10161089/ https://www.ncbi.nlm.nih.gov/pubmed/37098069 http://dx.doi.org/10.1073/pnas.2216587120 |
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