Early Endosomes Act as Local Exocytosis Hubs to Repair Endothelial Membrane Damage (Adv. Sci. 13/2023)

Plasma Membrane Resealing Endothelial cells (yellow) comprise the inner lining of blood vessels. Following laser‐induced injury of their plasma membrane, the membrane wound must be repaired to prevent cell death. This is achieved by early endosomes (red circles), compartments involved in conventiona...

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Autores principales: Raj, Nikita, Greune, Lilo, Kahms, Martin, Mildner, Karina, Franzkoch, Rico, Psathaki, Olympia Ekaterini, Zobel, Thomas, Zeuschner, Dagmar, Klingauf, Jürgen, Gerke, Volker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
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Frontispiece
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10161106/
http://dx.doi.org/10.1002/advs.202370078
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author Raj, Nikita
Greune, Lilo
Kahms, Martin
Mildner, Karina
Franzkoch, Rico
Psathaki, Olympia Ekaterini
Zobel, Thomas
Zeuschner, Dagmar
Klingauf, Jürgen
Gerke, Volker
author_facet Raj, Nikita
Greune, Lilo
Kahms, Martin
Mildner, Karina
Franzkoch, Rico
Psathaki, Olympia Ekaterini
Zobel, Thomas
Zeuschner, Dagmar
Klingauf, Jürgen
Gerke, Volker
author_sort Raj, Nikita
collection PubMed
description Plasma Membrane Resealing Endothelial cells (yellow) comprise the inner lining of blood vessels. Following laser‐induced injury of their plasma membrane, the membrane wound must be repaired to prevent cell death. This is achieved by early endosomes (red circles), compartments involved in conventional endocytic transport, which are repurposed for wound repair. They undergo Ca(2+)‐dependent exocytosis to provide membrane for resealing of the wound. More details can be found in article number 2300244 by Volker Gerke and co‐workers. [Image: see text]
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spelling pubmed-101611062023-05-06 Early Endosomes Act as Local Exocytosis Hubs to Repair Endothelial Membrane Damage (Adv. Sci. 13/2023) Raj, Nikita Greune, Lilo Kahms, Martin Mildner, Karina Franzkoch, Rico Psathaki, Olympia Ekaterini Zobel, Thomas Zeuschner, Dagmar Klingauf, Jürgen Gerke, Volker Adv Sci (Weinh) Frontispiece Plasma Membrane Resealing Endothelial cells (yellow) comprise the inner lining of blood vessels. Following laser‐induced injury of their plasma membrane, the membrane wound must be repaired to prevent cell death. This is achieved by early endosomes (red circles), compartments involved in conventional endocytic transport, which are repurposed for wound repair. They undergo Ca(2+)‐dependent exocytosis to provide membrane for resealing of the wound. More details can be found in article number 2300244 by Volker Gerke and co‐workers. [Image: see text] John Wiley and Sons Inc. 2023-05-05 /pmc/articles/PMC10161106/ http://dx.doi.org/10.1002/advs.202370078 Text en © 2023 Wiley‐VCH GmbH https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Frontispiece
Raj, Nikita
Greune, Lilo
Kahms, Martin
Mildner, Karina
Franzkoch, Rico
Psathaki, Olympia Ekaterini
Zobel, Thomas
Zeuschner, Dagmar
Klingauf, Jürgen
Gerke, Volker
Early Endosomes Act as Local Exocytosis Hubs to Repair Endothelial Membrane Damage (Adv. Sci. 13/2023)
title Early Endosomes Act as Local Exocytosis Hubs to Repair Endothelial Membrane Damage (Adv. Sci. 13/2023)
title_full Early Endosomes Act as Local Exocytosis Hubs to Repair Endothelial Membrane Damage (Adv. Sci. 13/2023)
title_fullStr Early Endosomes Act as Local Exocytosis Hubs to Repair Endothelial Membrane Damage (Adv. Sci. 13/2023)
title_full_unstemmed Early Endosomes Act as Local Exocytosis Hubs to Repair Endothelial Membrane Damage (Adv. Sci. 13/2023)
title_short Early Endosomes Act as Local Exocytosis Hubs to Repair Endothelial Membrane Damage (Adv. Sci. 13/2023)
title_sort early endosomes act as local exocytosis hubs to repair endothelial membrane damage (adv. sci. 13/2023)
topic Frontispiece
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10161106/
http://dx.doi.org/10.1002/advs.202370078
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