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Ovarian Carcinosarcoma and Response to Immunotherapy
Ovarian carcinosarcoma (OCS) is an uncommon and highly aggressive subtype of ovarian cancer. This form of cancer is characterized by limited treatment options and a poor prognosis. In this report, we present a case study of a 64-year-old female diagnosed with stage III OCS, who underwent debulking s...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10161148/ https://www.ncbi.nlm.nih.gov/pubmed/37153309 http://dx.doi.org/10.7759/cureus.37149 |
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author | Daniyal, Muhammad Polani, Anamm S Canary, Marcy |
author_facet | Daniyal, Muhammad Polani, Anamm S Canary, Marcy |
author_sort | Daniyal, Muhammad |
collection | PubMed |
description | Ovarian carcinosarcoma (OCS) is an uncommon and highly aggressive subtype of ovarian cancer. This form of cancer is characterized by limited treatment options and a poor prognosis. In this report, we present a case study of a 64-year-old female diagnosed with stage III OCS, who underwent debulking surgery and adjuvant chemotherapy, followed by immunotherapy, with encouraging outcomes. Despite the availability of diverse chemotherapy options, the prognosis for patients with OCS remains grim. However, the present case study of a 64-year-old female with OCS illustrates the promising outcomes achieved with immunotherapy. Additionally, this case highlights the significance of microsatellite instability testing in guiding treatment decisions for ovarian cancers of this nature. |
format | Online Article Text |
id | pubmed-10161148 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-101611482023-05-06 Ovarian Carcinosarcoma and Response to Immunotherapy Daniyal, Muhammad Polani, Anamm S Canary, Marcy Cureus Genetics Ovarian carcinosarcoma (OCS) is an uncommon and highly aggressive subtype of ovarian cancer. This form of cancer is characterized by limited treatment options and a poor prognosis. In this report, we present a case study of a 64-year-old female diagnosed with stage III OCS, who underwent debulking surgery and adjuvant chemotherapy, followed by immunotherapy, with encouraging outcomes. Despite the availability of diverse chemotherapy options, the prognosis for patients with OCS remains grim. However, the present case study of a 64-year-old female with OCS illustrates the promising outcomes achieved with immunotherapy. Additionally, this case highlights the significance of microsatellite instability testing in guiding treatment decisions for ovarian cancers of this nature. Cureus 2023-04-05 /pmc/articles/PMC10161148/ /pubmed/37153309 http://dx.doi.org/10.7759/cureus.37149 Text en Copyright © 2023, Daniyal et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Genetics Daniyal, Muhammad Polani, Anamm S Canary, Marcy Ovarian Carcinosarcoma and Response to Immunotherapy |
title | Ovarian Carcinosarcoma and Response to Immunotherapy |
title_full | Ovarian Carcinosarcoma and Response to Immunotherapy |
title_fullStr | Ovarian Carcinosarcoma and Response to Immunotherapy |
title_full_unstemmed | Ovarian Carcinosarcoma and Response to Immunotherapy |
title_short | Ovarian Carcinosarcoma and Response to Immunotherapy |
title_sort | ovarian carcinosarcoma and response to immunotherapy |
topic | Genetics |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10161148/ https://www.ncbi.nlm.nih.gov/pubmed/37153309 http://dx.doi.org/10.7759/cureus.37149 |
work_keys_str_mv | AT daniyalmuhammad ovariancarcinosarcomaandresponsetoimmunotherapy AT polanianamms ovariancarcinosarcomaandresponsetoimmunotherapy AT canarymarcy ovariancarcinosarcomaandresponsetoimmunotherapy |