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Ovarian Carcinosarcoma and Response to Immunotherapy

Ovarian carcinosarcoma (OCS) is an uncommon and highly aggressive subtype of ovarian cancer. This form of cancer is characterized by limited treatment options and a poor prognosis. In this report, we present a case study of a 64-year-old female diagnosed with stage III OCS, who underwent debulking s...

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Detalles Bibliográficos
Autores principales: Daniyal, Muhammad, Polani, Anamm S, Canary, Marcy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10161148/
https://www.ncbi.nlm.nih.gov/pubmed/37153309
http://dx.doi.org/10.7759/cureus.37149
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author Daniyal, Muhammad
Polani, Anamm S
Canary, Marcy
author_facet Daniyal, Muhammad
Polani, Anamm S
Canary, Marcy
author_sort Daniyal, Muhammad
collection PubMed
description Ovarian carcinosarcoma (OCS) is an uncommon and highly aggressive subtype of ovarian cancer. This form of cancer is characterized by limited treatment options and a poor prognosis. In this report, we present a case study of a 64-year-old female diagnosed with stage III OCS, who underwent debulking surgery and adjuvant chemotherapy, followed by immunotherapy, with encouraging outcomes. Despite the availability of diverse chemotherapy options, the prognosis for patients with OCS remains grim. However, the present case study of a 64-year-old female with OCS illustrates the promising outcomes achieved with immunotherapy. Additionally, this case highlights the significance of microsatellite instability testing in guiding treatment decisions for ovarian cancers of this nature.
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spelling pubmed-101611482023-05-06 Ovarian Carcinosarcoma and Response to Immunotherapy Daniyal, Muhammad Polani, Anamm S Canary, Marcy Cureus Genetics Ovarian carcinosarcoma (OCS) is an uncommon and highly aggressive subtype of ovarian cancer. This form of cancer is characterized by limited treatment options and a poor prognosis. In this report, we present a case study of a 64-year-old female diagnosed with stage III OCS, who underwent debulking surgery and adjuvant chemotherapy, followed by immunotherapy, with encouraging outcomes. Despite the availability of diverse chemotherapy options, the prognosis for patients with OCS remains grim. However, the present case study of a 64-year-old female with OCS illustrates the promising outcomes achieved with immunotherapy. Additionally, this case highlights the significance of microsatellite instability testing in guiding treatment decisions for ovarian cancers of this nature. Cureus 2023-04-05 /pmc/articles/PMC10161148/ /pubmed/37153309 http://dx.doi.org/10.7759/cureus.37149 Text en Copyright © 2023, Daniyal et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Genetics
Daniyal, Muhammad
Polani, Anamm S
Canary, Marcy
Ovarian Carcinosarcoma and Response to Immunotherapy
title Ovarian Carcinosarcoma and Response to Immunotherapy
title_full Ovarian Carcinosarcoma and Response to Immunotherapy
title_fullStr Ovarian Carcinosarcoma and Response to Immunotherapy
title_full_unstemmed Ovarian Carcinosarcoma and Response to Immunotherapy
title_short Ovarian Carcinosarcoma and Response to Immunotherapy
title_sort ovarian carcinosarcoma and response to immunotherapy
topic Genetics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10161148/
https://www.ncbi.nlm.nih.gov/pubmed/37153309
http://dx.doi.org/10.7759/cureus.37149
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AT canarymarcy ovariancarcinosarcomaandresponsetoimmunotherapy