Multiplex gene knockout raises Ala-Gln production by Escherichia coli expressing amino acid ester acyltransferase

ABSTRACT: L-Alanyl-L-Glutamine (Ala-Gln) is a common parenteral nutritional supplement. In our previous study, the recombinant whole-cell catalyst Escherichia coli BL21(DE3) overexpressing α-amino acid ester acyltransferase (BPA) to produce Ala-Gln has high activity and has been applied to large-sca...

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Detalles Bibliográficos
Autores principales: Jing, Zhanyu, Xu, Jian, Liu, Jia, Du, Cong, Qi, Jiakun, Fan, Chao, Li, Yimin, Yuan, Wenjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Biotechnological Products and Process Engineering
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10161157/
https://www.ncbi.nlm.nih.gov/pubmed/37145161
http://dx.doi.org/10.1007/s00253-023-12550-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10161157/
https://www.ncbi.nlm.nih.gov/pubmed/37145161
http://dx.doi.org/10.1007/s00253-023-12550-z

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