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Regiodivergent Nucleophilic Fluorination under Hydrogen Bonding Catalysis: A Computational and Experimental Study
[Image: see text] The controlled programming of regiochemical outcomes in nucleophilic fluorination reactions with alkali metal fluoride is a problem yet to be solved. Herein, two synergistic approaches exploiting hydrogen bonding catalysis are presented. First, we demonstrate that modulating the ch...
Autores principales: | Horwitz, Matthew A., Dürr, Alexander B., Afratis, Konstantinos, Chen, Zijun, Soika, Julia, Christensen, Kirsten E., Fushimi, Makoto, Paton, Robert S., Gouverneur, Véronique |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10161234/ https://www.ncbi.nlm.nih.gov/pubmed/37079853 http://dx.doi.org/10.1021/jacs.3c01303 |
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