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A novel multi-component protein vaccine ECP001 containing a protein polypeptide antigen nPstS1 riching in T-cell epitopes showed good immunogenicity and protection in mice
Tuberculosis (TB) is an infectious disease that seriously affects human health. Until now, the only anti-TB vaccine approved for use is the live attenuated Mycobacterium bovis (M. bovis) vaccine — BCG vaccine, but its protective efficacy is relatively low and does not provide satisfactory protection...
Autores principales: | Yu, Jinjie, Fan, Xueting, Luan, Xiuli, Wang, Ruihuan, Cao, Bin, Qian, Chengyu, Li, Guilian, Li, Machao, Zhao, Xiuqin, Liu, Haican, Wan, Kanglin, Yuan, Xiuqin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10161251/ https://www.ncbi.nlm.nih.gov/pubmed/37153610 http://dx.doi.org/10.3389/fimmu.2023.1138818 |
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