The relation between dietary zinc and immune status in saudi adults

Although there is an increased interest in zinc intake and its role in boosting immunity, to our knowledge, no studies have investigated the relationship between dietary zinc intake and immunity in Saudi adults. This cross-sectional study aimed to measure the extent to which the dietary zinc impacted the immune health of 252 Saudi adults aged 18 years and above. Immune health was assessed using the Immune Status Questionnaire (ISQ), and dietary zinc intake was estimated using an adapted zinc-specific version of the Saudi Food Frequency Questionnaire (SFFQ). Three scores were calculated for use in the statistical analyses (zinc intake score, immune status score, and health status score). A linear regression analysis was used to investigate the association between the dietary zinc intake and immune and health status scores. The means of dietary zinc intake, ISQ, and health status scores were 46.94, 7.10, and 7.84, respectively. We found that a high zinc intake score was directly associated with immune status score (p = 0.006) but was not associated with the health status score. The association remained significant after controlling for socio-demographic factors. Further studies are needed to confirm these findings.