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Exosomes derived from synovial fibroblasts from patients with rheumatoid arthritis promote macrophage migration that can be suppressed by miR-124-3p

OBJECTIVES: Exosomes are potent vehicles for intercellular communication. Rheumatoid arthritis (RA) is a chronic systemic disease of unknown etiology. Local administration of miR-124 precursor to rats with adjuvant-induced arthritis suppresses systemic arthritis and bone destruction. Thus, exosomes...

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Detalles Bibliográficos
Autores principales: Nakamachi, Yuji, Uto, Kenichi, Hayashi, Shinya, Okano, Takaichi, Morinobu, Akio, Kuroda, Ryosuke, Kawano, Seiji, Saegusa, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10161379/
https://www.ncbi.nlm.nih.gov/pubmed/37151687
http://dx.doi.org/10.1016/j.heliyon.2023.e14986

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