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Exosomes derived from synovial fibroblasts from patients with rheumatoid arthritis promote macrophage migration that can be suppressed by miR-124-3p
OBJECTIVES: Exosomes are potent vehicles for intercellular communication. Rheumatoid arthritis (RA) is a chronic systemic disease of unknown etiology. Local administration of miR-124 precursor to rats with adjuvant-induced arthritis suppresses systemic arthritis and bone destruction. Thus, exosomes...
Autores principales: | Nakamachi, Yuji, Uto, Kenichi, Hayashi, Shinya, Okano, Takaichi, Morinobu, Akio, Kuroda, Ryosuke, Kawano, Seiji, Saegusa, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10161379/ https://www.ncbi.nlm.nih.gov/pubmed/37151687 http://dx.doi.org/10.1016/j.heliyon.2023.e14986 |
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