Human-associated bacteria adopt an unusual route for synthesizing 3-acetylated tetramates for environmental adaptation

BACKGROUND: Tetramates or tetramic acid-containing compounds (TACs) are a group of bioactive natural products featuring a pyrrolidine-2,4-dione ring acknowledged being closed via Dieckmann cyclization. The cariogenic Streptococcus mutans strains bearing a muc biosynthetic gene cluster (BGC) can synt...

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Detalles Bibliográficos
Autores principales: Zhang, Yuwei, Liao, Ge, Wang, Min, Zhang, Zhao, Liu, Liwei, Song, Yuqin, Wang, Dacheng, Hao, Tingting, Feng, Jie, Xia, Bin, Wang, Yixiang, Tang, Xiaoyu, Chen, Yihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10161427/
https://www.ncbi.nlm.nih.gov/pubmed/37147735
http://dx.doi.org/10.1186/s40168-023-01548-4

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