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The Warburg effect modulates DHODH role in ferroptosis: a review

Ferroptosis is an iron-dependent regulated cell death that suppresses tumor growth. It is activated by extensive peroxidation of membrane phospholipids caused by oxidative stress. GPX4, an antioxidant enzyme, reduces these peroxidized membrane phospholipids thereby inhibiting ferroptosis. This enzym...

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Detalles Bibliográficos
Autores principales: Amos, Alvan, Amos, Alex, Wu, Lirong, Xia, He
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10161480/
https://www.ncbi.nlm.nih.gov/pubmed/37147673
http://dx.doi.org/10.1186/s12964-022-01025-9