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Disheveled3 enhanced EMT and cancer stem-like cells properties via Wnt/β-catenin/c-Myc/SOX2 pathway in colorectal cancer

BACKGROUND: Epithelial-to-mesenchymal transition (EMT) and cancer stem-like cells (CSLCs) play crucial role in tumor metastasis and drug-resistance. Disheveled3 (DVL3) is involved in malignant behaviors of cancer. However, the role and potential mechanism of DVL3 remain elusive in EMT and CSLCs of c...

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Detalles Bibliográficos
Autores principales: Li, Zhengguang, Yang, Zhirong, Liu, Wei, Zhu, Wanglong, Yin, Lan, Han, Zhenyu, Xian, Yu, Wen, Jie, Tang, Hualong, Lin, Xinyue, Yang, Yuhan, Wang, Jingyi, Zhang, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10161491/
https://www.ncbi.nlm.nih.gov/pubmed/37147666
http://dx.doi.org/10.1186/s12967-023-04120-8