Targeting serine-glycine-one-carbon metabolism as a vulnerability in cancers

The serine-glycine-one-carbon (SGOC) metabolic pathway is critical for DNA methylation, histone methylation, and redox homeostasis, in addition to protein, lipid, and nucleotide biosynthesis. The SGOC pathway is a crucial metabolic network in tumorigenesis, wherein the outputs are required for cell...

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Detalles Bibliográficos
Autores principales: Sun, Wei, Liu, Ruochen, Gao, Xinyue, Lin, Zini, Tang, Hongao, Cui, Hongjuan, Zhao, Erhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10161514/
https://www.ncbi.nlm.nih.gov/pubmed/37147729
http://dx.doi.org/10.1186/s40364-023-00487-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10161514/
https://www.ncbi.nlm.nih.gov/pubmed/37147729
http://dx.doi.org/10.1186/s40364-023-00487-4

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