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A CRISPR interference strategy for gene expression silencing in multiple myeloma cell lines

BACKGROUND: Multiple myeloma (MM) is the second most common hematologic neoplasm which is characterized by proliferation and infiltration of plasmatic cells in the bone marrow. Currently, MM is considered incurable due to resistance to treatment. The CRISPR/Cas9 system has emerged as a powerful tool...

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Detalles Bibliográficos
Autores principales: Escrivá-Fernández, Josep, Cueto-Ureña, Cristina, Solana-Orts, Amalia, Lledó, Elisa, Ballester-Lurbe, Begoña, Poch, Enric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10161638/
https://www.ncbi.nlm.nih.gov/pubmed/37143063
http://dx.doi.org/10.1186/s13036-023-00347-7