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A CRISPR interference strategy for gene expression silencing in multiple myeloma cell lines
BACKGROUND: Multiple myeloma (MM) is the second most common hematologic neoplasm which is characterized by proliferation and infiltration of plasmatic cells in the bone marrow. Currently, MM is considered incurable due to resistance to treatment. The CRISPR/Cas9 system has emerged as a powerful tool...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10161638/ https://www.ncbi.nlm.nih.gov/pubmed/37143063 http://dx.doi.org/10.1186/s13036-023-00347-7 |