Mapping splice QTLs reveals distinct transcriptional and post-transcriptional regulatory variation of gene expression and identifies putative alternative splicing variation mediating complex trait variation in pigs

BACKGROUND: Alternative splicing is an important step in gene expression, generating multiple isoforms for the same genes and greatly expanding the diversity of proteomes. Genetic variation in alternative splicing contributes to phenotypic diversity in natural populations. However, the genetic basis...

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Detalles Bibliográficos
Autores principales: Zhang, Fei, Velez-Irizarry, Deborah, Ernst, Catherine W., Huang, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10161646/
https://www.ncbi.nlm.nih.gov/pubmed/37142954
http://dx.doi.org/10.1186/s12864-023-09314-4

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