Disseminated tuberculosis in rare association with hemophagocytic lymphocytosis - A case report from central India

Hemophagocytic Lymphohistiocytosis (HLH) is an uncommon, diverse and rare genetic hyper-inflammatory syndrome. HLH associated with tuberculosis (TB-HLH) has been described as a clinical and diagnostic quandary. The co-existence leads to significantly higher morbidity and mortality. Our case highligh...

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Autores principales: Gautam, Disha, Dadheech, Malti, Ingle, Vaibhav, Jayashankar, Erukkambattu, Purwar, Shashank, Maurya, Anand Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10161793/
https://www.ncbi.nlm.nih.gov/pubmed/37151652
http://dx.doi.org/10.1016/j.heliyon.2023.e15646
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author Gautam, Disha
Dadheech, Malti
Ingle, Vaibhav
Jayashankar, Erukkambattu
Purwar, Shashank
Maurya, Anand Kumar
author_facet Gautam, Disha
Dadheech, Malti
Ingle, Vaibhav
Jayashankar, Erukkambattu
Purwar, Shashank
Maurya, Anand Kumar
author_sort Gautam, Disha
collection PubMed
description Hemophagocytic Lymphohistiocytosis (HLH) is an uncommon, diverse and rare genetic hyper-inflammatory syndrome. HLH associated with tuberculosis (TB-HLH) has been described as a clinical and diagnostic quandary. The co-existence leads to significantly higher morbidity and mortality. Our case highlights the presence of disseminated tuberculosis and worsening of the case due to underlying hemophagocytic syndrome leading to rapid deterioration of patient prognosis. Prompt diagnosis and treatment remains help to improve patient management.
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spelling pubmed-101617932023-05-06 Disseminated tuberculosis in rare association with hemophagocytic lymphocytosis - A case report from central India Gautam, Disha Dadheech, Malti Ingle, Vaibhav Jayashankar, Erukkambattu Purwar, Shashank Maurya, Anand Kumar Heliyon Case Report Hemophagocytic Lymphohistiocytosis (HLH) is an uncommon, diverse and rare genetic hyper-inflammatory syndrome. HLH associated with tuberculosis (TB-HLH) has been described as a clinical and diagnostic quandary. The co-existence leads to significantly higher morbidity and mortality. Our case highlights the presence of disseminated tuberculosis and worsening of the case due to underlying hemophagocytic syndrome leading to rapid deterioration of patient prognosis. Prompt diagnosis and treatment remains help to improve patient management. Elsevier 2023-04-20 /pmc/articles/PMC10161793/ /pubmed/37151652 http://dx.doi.org/10.1016/j.heliyon.2023.e15646 Text en © 2023 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Gautam, Disha
Dadheech, Malti
Ingle, Vaibhav
Jayashankar, Erukkambattu
Purwar, Shashank
Maurya, Anand Kumar
Disseminated tuberculosis in rare association with hemophagocytic lymphocytosis - A case report from central India
title Disseminated tuberculosis in rare association with hemophagocytic lymphocytosis - A case report from central India
title_full Disseminated tuberculosis in rare association with hemophagocytic lymphocytosis - A case report from central India
title_fullStr Disseminated tuberculosis in rare association with hemophagocytic lymphocytosis - A case report from central India
title_full_unstemmed Disseminated tuberculosis in rare association with hemophagocytic lymphocytosis - A case report from central India
title_short Disseminated tuberculosis in rare association with hemophagocytic lymphocytosis - A case report from central India
title_sort disseminated tuberculosis in rare association with hemophagocytic lymphocytosis - a case report from central india
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10161793/
https://www.ncbi.nlm.nih.gov/pubmed/37151652
http://dx.doi.org/10.1016/j.heliyon.2023.e15646
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