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Metabolismo de los esfingolípidos y su relación con las enfermedades cardiovasculares, renales y metabólicas
Sphingolipids (sphingomyelin, glycolipids, gangliosides) are located in cell membranes, plasma, and lipoproteins. In patients with cardiovascular, renal, and metabolic diseases, the profile of sphingolipids and their metabolites (ceramide, sphingosine, and sphingosine-1-phosphate) is modified, and t...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Permanyer Publications
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10161840/ https://www.ncbi.nlm.nih.gov/pubmed/36757794 http://dx.doi.org/10.24875/ACM.21000333 |
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author | Hernández-Bello, Fernando Franco, Martha Pérez-Méndez, Óscar Donis-Maturano, Luis Zarco-Olvera, Gabriela Bautista-Pérez, Rocío |
author_facet | Hernández-Bello, Fernando Franco, Martha Pérez-Méndez, Óscar Donis-Maturano, Luis Zarco-Olvera, Gabriela Bautista-Pérez, Rocío |
author_sort | Hernández-Bello, Fernando |
collection | PubMed |
description | Sphingolipids (sphingomyelin, glycolipids, gangliosides) are located in cell membranes, plasma, and lipoproteins. In patients with cardiovascular, renal, and metabolic diseases, the profile of sphingolipids and their metabolites (ceramide, sphingosine, and sphingosine-1-phosphate) is modified, and these changes may explain the alterations in some cellular responses such as apoptosis. Furthermore, sphingosine and sphingosine-1-phosphate have been suggested to prevent COVID-19. This review also briefly mentions the techniques that allow us to study sphingolipids and their metabolites. |
format | Online Article Text |
id | pubmed-10161840 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Permanyer Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-101618402023-05-06 Metabolismo de los esfingolípidos y su relación con las enfermedades cardiovasculares, renales y metabólicas Hernández-Bello, Fernando Franco, Martha Pérez-Méndez, Óscar Donis-Maturano, Luis Zarco-Olvera, Gabriela Bautista-Pérez, Rocío Arch Cardiol Mex Artículo De Revisión Sphingolipids (sphingomyelin, glycolipids, gangliosides) are located in cell membranes, plasma, and lipoproteins. In patients with cardiovascular, renal, and metabolic diseases, the profile of sphingolipids and their metabolites (ceramide, sphingosine, and sphingosine-1-phosphate) is modified, and these changes may explain the alterations in some cellular responses such as apoptosis. Furthermore, sphingosine and sphingosine-1-phosphate have been suggested to prevent COVID-19. This review also briefly mentions the techniques that allow us to study sphingolipids and their metabolites. Permanyer Publications 2023 2023-02-02 /pmc/articles/PMC10161840/ /pubmed/36757794 http://dx.doi.org/10.24875/ACM.21000333 Text en Copyright: © 2023 Permanyer https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License |
spellingShingle | Artículo De Revisión Hernández-Bello, Fernando Franco, Martha Pérez-Méndez, Óscar Donis-Maturano, Luis Zarco-Olvera, Gabriela Bautista-Pérez, Rocío Metabolismo de los esfingolípidos y su relación con las enfermedades cardiovasculares, renales y metabólicas |
title | Metabolismo de los esfingolípidos y su relación con las enfermedades cardiovasculares, renales y metabólicas |
title_full | Metabolismo de los esfingolípidos y su relación con las enfermedades cardiovasculares, renales y metabólicas |
title_fullStr | Metabolismo de los esfingolípidos y su relación con las enfermedades cardiovasculares, renales y metabólicas |
title_full_unstemmed | Metabolismo de los esfingolípidos y su relación con las enfermedades cardiovasculares, renales y metabólicas |
title_short | Metabolismo de los esfingolípidos y su relación con las enfermedades cardiovasculares, renales y metabólicas |
title_sort | metabolismo de los esfingolípidos y su relación con las enfermedades cardiovasculares, renales y metabólicas |
topic | Artículo De Revisión |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10161840/ https://www.ncbi.nlm.nih.gov/pubmed/36757794 http://dx.doi.org/10.24875/ACM.21000333 |
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