(23R,23(1) S,25S)-23(1),26-Ep­oxy-23-ethyl­furost-20(22)-en-3β-ol

The title compound, C(29)H(46)O(3), is a steroid synthesized through a rearrangement of a sarsasapogenin derivative in acidic medium. The newly formed ring F is a tetra­hydro-2H-pyran heterocycle substituted by two methyl groups placed in equatorial positions. This ring displays a chair conformation...

Descripción completa

Detalles Bibliográficos
Autores principales: Guerrero-Luna, Gabriel, Hernández-Linares, María-Guadalupe, Cárdenas García, Maura, Bernès, Sylvain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2023
Materias:
Data Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10162030/
https://www.ncbi.nlm.nih.gov/pubmed/37151203
http://dx.doi.org/10.1107/S2414314623003449
_version_ 1785037618577145856
author Guerrero-Luna, Gabriel
Hernández-Linares, María-Guadalupe
Cárdenas García, Maura
Bernès, Sylvain
author_facet Guerrero-Luna, Gabriel
Hernández-Linares, María-Guadalupe
Cárdenas García, Maura
Bernès, Sylvain
author_sort Guerrero-Luna, Gabriel
collection PubMed
description The title compound, C(29)H(46)O(3), is a steroid synthesized through a rearrangement of a sarsasapogenin derivative in acidic medium. The newly formed ring F is a tetra­hydro-2H-pyran heterocycle substituted by two methyl groups placed in equatorial positions. This ring displays a chair conformation, while di­hydro­furan ring E, to which it is bonded, has an envelope conformation. The mol­ecules are associated by weak O—H⋯O hydrogen bonds to form chains running in the [101] direction in the crystal. [Image: see text]
format Online
Article
Text
id pubmed-10162030
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher International Union of Crystallography
record_format MEDLINE/PubMed
spelling pubmed-101620302023-05-06 (23R,23(1) S,25S)-23(1),26-Ep­oxy-23-ethyl­furost-20(22)-en-3β-ol Guerrero-Luna, Gabriel Hernández-Linares, María-Guadalupe Cárdenas García, Maura Bernès, Sylvain IUCrdata Data Reports The title compound, C(29)H(46)O(3), is a steroid synthesized through a rearrangement of a sarsasapogenin derivative in acidic medium. The newly formed ring F is a tetra­hydro-2H-pyran heterocycle substituted by two methyl groups placed in equatorial positions. This ring displays a chair conformation, while di­hydro­furan ring E, to which it is bonded, has an envelope conformation. The mol­ecules are associated by weak O—H⋯O hydrogen bonds to form chains running in the [101] direction in the crystal. [Image: see text] International Union of Crystallography 2023-04-21 /pmc/articles/PMC10162030/ /pubmed/37151203 http://dx.doi.org/10.1107/S2414314623003449 Text en © Guerrero-Luna et al. 2023 https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution (CC-BY) Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Data Reports
Guerrero-Luna, Gabriel
Hernández-Linares, María-Guadalupe
Cárdenas García, Maura
Bernès, Sylvain
(23R,23(1) S,25S)-23(1),26-Ep­oxy-23-ethyl­furost-20(22)-en-3β-ol
title (23R,23(1) S,25S)-23(1),26-Ep­oxy-23-ethyl­furost-20(22)-en-3β-ol
title_full (23R,23(1) S,25S)-23(1),26-Ep­oxy-23-ethyl­furost-20(22)-en-3β-ol
title_fullStr (23R,23(1) S,25S)-23(1),26-Ep­oxy-23-ethyl­furost-20(22)-en-3β-ol
title_full_unstemmed (23R,23(1) S,25S)-23(1),26-Ep­oxy-23-ethyl­furost-20(22)-en-3β-ol
title_short (23R,23(1) S,25S)-23(1),26-Ep­oxy-23-ethyl­furost-20(22)-en-3β-ol
title_sort (23r,23(1) s,25s)-23(1),26-ep­oxy-23-ethyl­furost-20(22)-en-3β-ol
topic Data Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10162030/
https://www.ncbi.nlm.nih.gov/pubmed/37151203
http://dx.doi.org/10.1107/S2414314623003449
work_keys_str_mv AT guerrerolunagabriel 23r231s25s23126epoxy23ethylfurost2022en3bol
AT hernandezlinaresmariaguadalupe 23r231s25s23126epoxy23ethylfurost2022en3bol
AT cardenasgarciamaura 23r231s25s23126epoxy23ethylfurost2022en3bol
AT bernessylvain 23r231s25s23126epoxy23ethylfurost2022en3bol

Ejemplares similares