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Mechanosensitive mTORC2 independently coordinates leading and trailing edge polarity programs during neutrophil migration
By acting both upstream of and downstream from biochemical organizers of the cytoskeleton, physical forces function as central integrators of cell shape and movement. Here we use a combination of genetic, pharmacological, and optogenetic perturbations to probe the role of the conserved mechanosensit...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10162419/ https://www.ncbi.nlm.nih.gov/pubmed/36857159 http://dx.doi.org/10.1091/mbc.E22-05-0191 |