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Remodeling of E-cadherin subcellular localization during cell dissemination

Given the role of E-cadherin (E-cad) in holding epithelial cells together, an inverse relationship between E-cad levels and cell invasion during the epithelial-mesenchymal transition and cancer metastasis has been well recognized. Here we report that E-cad is necessary for the invasiveness of Ras(V1...

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Detalles Bibliográficos
Autores principales: Cabrera, Alejandra J. H., Gumbiner, Barry M., Kwon, Young V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10162421/
https://www.ncbi.nlm.nih.gov/pubmed/36989029
http://dx.doi.org/10.1091/mbc.E23-03-0087