Cargando…
Supervised breast cancer prediction using integrated dimensionality reduction convolutional neural network
OBJECTIVES: Breast cancer is a major health problem with high mortality rates. Early detection of breast cancer will promote treatment. A technology that determines whether a tumor is benign desirable. This article introduces a new method in which deep learning is used to classify breast cancer. MET...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10162536/ https://www.ncbi.nlm.nih.gov/pubmed/37146014 http://dx.doi.org/10.1371/journal.pone.0282350 |
_version_ | 1785037715074449408 |
---|---|
author | Xu, HuanQing Shao, Xian Hui, Shiji Jin, Li |
author_facet | Xu, HuanQing Shao, Xian Hui, Shiji Jin, Li |
author_sort | Xu, HuanQing |
collection | PubMed |
description | OBJECTIVES: Breast cancer is a major health problem with high mortality rates. Early detection of breast cancer will promote treatment. A technology that determines whether a tumor is benign desirable. This article introduces a new method in which deep learning is used to classify breast cancer. METHODS: A new computer-aided detection (CAD) system is presented to classify benign and malignant masses in breast tumor cell samples. In the CAD system, (1) for the pathological data of unbalanced tumors, the training results are biased towards the side with the larger number of samples. This paper uses a Conditional Deep Convolution Generative Adversarial Network (CDCGAN) method to generate small samples by orientation data set to solve the imbalance problem of collected data. (2) For the high-dimensional data redundancy problem, this paper proposes an integrated dimension reduction convolutional neural network (IDRCNN) model, which solves the high-dimensional data dimension reduction problem of breast cancer and extracts effective features. The subsequent classifier found that by using the IDRCNN model proposed in this paper, the accuracy of the model was improved. RESULTS: Experimental results show that IDRCNN combined with the model of CDCGAN model has superior classification performance than existing methods, as revealed by sensitivity, area under the curve (AUC), ROC curve and accuracy, recall, sensitivity, specificity, precision,PPV,NPV and f-values analysis. CONCLUSION: This paper proposes a Conditional Deep Convolution Generative Adversarial Network (CDCGAN) which can solve the imbalance problem of manually collected data by directionally generating small sample data sets. And an integrated dimension reduction convolutional neural network (IDRCNN) model, which solves the high-dimensional data dimension reduction problem of breast cancer and extracts effective features. |
format | Online Article Text |
id | pubmed-10162536 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-101625362023-05-06 Supervised breast cancer prediction using integrated dimensionality reduction convolutional neural network Xu, HuanQing Shao, Xian Hui, Shiji Jin, Li PLoS One Research Article OBJECTIVES: Breast cancer is a major health problem with high mortality rates. Early detection of breast cancer will promote treatment. A technology that determines whether a tumor is benign desirable. This article introduces a new method in which deep learning is used to classify breast cancer. METHODS: A new computer-aided detection (CAD) system is presented to classify benign and malignant masses in breast tumor cell samples. In the CAD system, (1) for the pathological data of unbalanced tumors, the training results are biased towards the side with the larger number of samples. This paper uses a Conditional Deep Convolution Generative Adversarial Network (CDCGAN) method to generate small samples by orientation data set to solve the imbalance problem of collected data. (2) For the high-dimensional data redundancy problem, this paper proposes an integrated dimension reduction convolutional neural network (IDRCNN) model, which solves the high-dimensional data dimension reduction problem of breast cancer and extracts effective features. The subsequent classifier found that by using the IDRCNN model proposed in this paper, the accuracy of the model was improved. RESULTS: Experimental results show that IDRCNN combined with the model of CDCGAN model has superior classification performance than existing methods, as revealed by sensitivity, area under the curve (AUC), ROC curve and accuracy, recall, sensitivity, specificity, precision,PPV,NPV and f-values analysis. CONCLUSION: This paper proposes a Conditional Deep Convolution Generative Adversarial Network (CDCGAN) which can solve the imbalance problem of manually collected data by directionally generating small sample data sets. And an integrated dimension reduction convolutional neural network (IDRCNN) model, which solves the high-dimensional data dimension reduction problem of breast cancer and extracts effective features. Public Library of Science 2023-05-05 /pmc/articles/PMC10162536/ /pubmed/37146014 http://dx.doi.org/10.1371/journal.pone.0282350 Text en © 2023 Xu et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Xu, HuanQing Shao, Xian Hui, Shiji Jin, Li Supervised breast cancer prediction using integrated dimensionality reduction convolutional neural network |
title | Supervised breast cancer prediction using integrated dimensionality reduction convolutional neural network |
title_full | Supervised breast cancer prediction using integrated dimensionality reduction convolutional neural network |
title_fullStr | Supervised breast cancer prediction using integrated dimensionality reduction convolutional neural network |
title_full_unstemmed | Supervised breast cancer prediction using integrated dimensionality reduction convolutional neural network |
title_short | Supervised breast cancer prediction using integrated dimensionality reduction convolutional neural network |
title_sort | supervised breast cancer prediction using integrated dimensionality reduction convolutional neural network |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10162536/ https://www.ncbi.nlm.nih.gov/pubmed/37146014 http://dx.doi.org/10.1371/journal.pone.0282350 |
work_keys_str_mv | AT xuhuanqing supervisedbreastcancerpredictionusingintegrateddimensionalityreductionconvolutionalneuralnetwork AT shaoxian supervisedbreastcancerpredictionusingintegrateddimensionalityreductionconvolutionalneuralnetwork AT huishiji supervisedbreastcancerpredictionusingintegrateddimensionalityreductionconvolutionalneuralnetwork AT jinli supervisedbreastcancerpredictionusingintegrateddimensionalityreductionconvolutionalneuralnetwork |