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Crystalline silica-exposed human lung epithelial cells presented enhanced anchorage-independent growth with upregulated expression of BRD4 and EZH2 in autocrine and paracrine manners

Crystalline silica-induced inflammation possibly facilitates carcinogenesis. Here, we investigated its effect on lung epithelium damage. We prepared conditioned media of immortalized human bronchial epithelial cell lines (hereinafter bronchial cell lines) NL20, BEAS-2B, and 16HBE14o- pre-exposed to...

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Detalles Bibliográficos
Autores principales:	Katabami, Motoo, Kinoshita, Ichiro, Ariga, Shin, Shimizu, Yasushi, Dosaka-Akita, Hirotoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10162546/ https://www.ncbi.nlm.nih.gov/pubmed/37146018 http://dx.doi.org/10.1371/journal.pone.0285354

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