Jo-1 Antibodies From Myositis Induce Complement-Dependent Cytotoxicity and TREM-1 Upregulation in Muscle Endothelial Cells

BACKGROUND AND OBJECTIVES: Muscle microangiopathy due to dysfunction of endothelial cells because of inflammation is a critical hallmark of dermatomyositis (DM); however, its pathomechanism remains unclear. The aim of this study was to evaluate the effect of immunogloblin G (IgG) from patients with...

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Detalles Bibliográficos
Autores principales: Honda, Masaya, Shimizu, Fumitaka, Sato, Ryota, Mizukami, Yoichi, Watanabe, Kenji, Takeshita, Yukio, Maeda, Toshihiko, Koga, Michiaki, Kanda, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10162704/
https://www.ncbi.nlm.nih.gov/pubmed/37147138
http://dx.doi.org/10.1212/NXI.0000000000200116

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