Segmental Collagenoma in Tuberous Sclerosis – Think Beyond the Skin: A Rare Case Report

Collagenomas are connective tissue nevi characterized by an imbalance in the distribution and amount of collagen in the extracellular matrix. Shagreen patch, a collagenoma of tuberous sclerosis, is a classical finding in this genodermatosis (Tuberous Sclerosis). Though the prototypical lesion is a s...

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Autores principales: Nagarajan, Ashok Kumar, Manoharan, Krishnaswamy, Moozhiyil, Shreya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10162764/
https://www.ncbi.nlm.nih.gov/pubmed/37151256
http://dx.doi.org/10.4103/ijd.ijd_1038_20
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author Nagarajan, Ashok Kumar
Manoharan, Krishnaswamy
Moozhiyil, Shreya
author_facet Nagarajan, Ashok Kumar
Manoharan, Krishnaswamy
Moozhiyil, Shreya
author_sort Nagarajan, Ashok Kumar
collection PubMed
description Collagenomas are connective tissue nevi characterized by an imbalance in the distribution and amount of collagen in the extracellular matrix. Shagreen patch, a collagenoma of tuberous sclerosis, is a classical finding in this genodermatosis (Tuberous Sclerosis). Though the prototypical lesion is a shagreen patch, some individuals manifest only small collagenomas, and these can hinder a diagnosis of tuberous sclerosis and thus mask underlying systemic involvement as was seen in this case we have reported, wherein a 22-year-old male presented with segmental collagenomas over the face and calcified subependymal nodules of the brain on further investigation.
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spelling pubmed-101627642023-05-06 Segmental Collagenoma in Tuberous Sclerosis – Think Beyond the Skin: A Rare Case Report Nagarajan, Ashok Kumar Manoharan, Krishnaswamy Moozhiyil, Shreya Indian J Dermatol Case Report Collagenomas are connective tissue nevi characterized by an imbalance in the distribution and amount of collagen in the extracellular matrix. Shagreen patch, a collagenoma of tuberous sclerosis, is a classical finding in this genodermatosis (Tuberous Sclerosis). Though the prototypical lesion is a shagreen patch, some individuals manifest only small collagenomas, and these can hinder a diagnosis of tuberous sclerosis and thus mask underlying systemic involvement as was seen in this case we have reported, wherein a 22-year-old male presented with segmental collagenomas over the face and calcified subependymal nodules of the brain on further investigation. Wolters Kluwer - Medknow 2023 /pmc/articles/PMC10162764/ /pubmed/37151256 http://dx.doi.org/10.4103/ijd.ijd_1038_20 Text en Copyright: © 2023 Indian Journal of Dermatology https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Nagarajan, Ashok Kumar
Manoharan, Krishnaswamy
Moozhiyil, Shreya
Segmental Collagenoma in Tuberous Sclerosis – Think Beyond the Skin: A Rare Case Report
title Segmental Collagenoma in Tuberous Sclerosis – Think Beyond the Skin: A Rare Case Report
title_full Segmental Collagenoma in Tuberous Sclerosis – Think Beyond the Skin: A Rare Case Report
title_fullStr Segmental Collagenoma in Tuberous Sclerosis – Think Beyond the Skin: A Rare Case Report
title_full_unstemmed Segmental Collagenoma in Tuberous Sclerosis – Think Beyond the Skin: A Rare Case Report
title_short Segmental Collagenoma in Tuberous Sclerosis – Think Beyond the Skin: A Rare Case Report
title_sort segmental collagenoma in tuberous sclerosis – think beyond the skin: a rare case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10162764/
https://www.ncbi.nlm.nih.gov/pubmed/37151256
http://dx.doi.org/10.4103/ijd.ijd_1038_20
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AT moozhiyilshreya segmentalcollagenomaintuberoussclerosisthinkbeyondtheskinararecasereport

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