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PASK links cellular energy metabolism with a mitotic self-renewal network to establish differentiation competence

Quiescent stem cells are activated in response to a mechanical or chemical injury to their tissue niche. Activated cells rapidly generate a heterogeneous progenitor population that regenerates the damaged tissues. While the transcriptional cadence that generates heterogeneity is known, the metabolic...

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Detalles Bibliográficos
Autores principales: Xiao, Michael, Wu, Chia-Hua, Meek, Graham, Kelly, Brian, Castillo, Dara Buendia, Young, Lyndsay EA, Martire, Sara, Dhungel, Sajina, McCauley, Elizabeth, Saha, Purbita, Dube, Altair L, Gentry, Matthew S, Banaszynski, Laura A, Sun, Ramon C, Kikani, Chintan K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10162801/
https://www.ncbi.nlm.nih.gov/pubmed/37052079
http://dx.doi.org/10.7554/eLife.81717