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A pH-dependent cluster of charges in a conserved cryptic pocket on flaviviral envelopes

Flaviviruses are enveloped viruses which include human pathogens that are predominantly transmitted by mosquitoes and ticks. Some, such as dengue virus, exhibit the phenomenon of antibody-dependent enhancement (ADE) of disease, making vaccine-based routes of fighting infections problematic. The pH-d...

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Detalles Bibliográficos
Autores principales: Zuzic, Lorena, Marzinek, Jan K, Anand, Ganesh S, Warwicker, Jim, Bond, Peter J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10162804/
https://www.ncbi.nlm.nih.gov/pubmed/37144875
http://dx.doi.org/10.7554/eLife.82447

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