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A pH-dependent cluster of charges in a conserved cryptic pocket on flaviviral envelopes
Flaviviruses are enveloped viruses which include human pathogens that are predominantly transmitted by mosquitoes and ticks. Some, such as dengue virus, exhibit the phenomenon of antibody-dependent enhancement (ADE) of disease, making vaccine-based routes of fighting infections problematic. The pH-d...
Autores principales: | Zuzic, Lorena, Marzinek, Jan K, Anand, Ganesh S, Warwicker, Jim, Bond, Peter J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10162804/ https://www.ncbi.nlm.nih.gov/pubmed/37144875 http://dx.doi.org/10.7554/eLife.82447 |
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