CREPE: a Shiny app for transcription factor cataloguing

SUMMARY: Transcription factors (TFs) are proteins that directly interpret the genome to regulate gene expression and determine cellular phenotypes. TF identification is a common first step in unraveling gene regulatory networks. We present CREPE, an R Shiny app to catalogue and annotate TFs. CREPE was benchmarked against curated human TF datasets. Next, we use CREPE to explore the TF repertoires of Heliconius erato and Heliconius melpomene butterflies. AVAILABILITY AND IMPLEMENTATION: CREPE is available as a Shiny app package available at GitHub (github.com/dirostri/CREPE). SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics Advances online.