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miR-137–LAPTM4B regulates cytoskeleton organization and cancer metastasis via the RhoA-LIMK-Cofilin pathway in osteosarcoma

Osteosarcoma (OS) is a rare malignant bone tumor but is one leading cause of cancer mortality in childhood and adolescence. Cancer metastasis accounts for the primary reason for treatment failure in OS patients. The dynamic organization of the cytoskeleton is fundamental for cell motility, migration...

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Detalles Bibliográficos
Autores principales: Yan, Ruyu, Liu, Dan, Wang, Junjie, Liu, Minxia, Guo, Hongjuan, Bai, Jing, Yang, Shuo, Chang, Jun, Yao, Zhihong, Yang, Zuozhang, Blom, Tomas, Zhou, Kecheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163001/
https://www.ncbi.nlm.nih.gov/pubmed/37147294
http://dx.doi.org/10.1038/s41389-023-00471-5

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