Self-organized yolk sac-like organoids allow for scalable generation of multipotent hematopoietic progenitor cells from induced pluripotent stem cells

Although the differentiation of human induced pluripotent stem cells (hiPSCs) into various types of blood cells has been well established, approaches for clinical-scale production of multipotent hematopoietic progenitor cells (HPCs) remain challenging. We found that hiPSCs cocultured with stromal ce...

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Detalles Bibliográficos
Autores principales: Tamaoki, Naritaka, Siebert, Stefan, Maeda, Takuya, Ha, Ngoc-Han, Good, Meghan L., Huang, Yin, Vodnala, Suman K., Haro-Mora, Juan J., Uchida, Naoya, Tisdale, John F., Sweeney, Colin L., Choi, Uimook, Brault, Julie, Koontz, Sherry, Malech, Harry L., Yamazaki, Yasuhiro, Isonaka, Risa, Goldstein, David S., Kimura, Masaki, Takebe, Takanori, Zou, Jizhong, Stroncek, David F., Robey, Pamela G., Kruhlak, Michael J., Restifo, Nicholas P., Vizcardo, Raul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163025/
https://www.ncbi.nlm.nih.gov/pubmed/37159663
http://dx.doi.org/10.1016/j.crmeth.2023.100460

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