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Generation of left ventricle-like cardiomyocytes with improved structural, functional, and metabolic maturity from human pluripotent stem cells

Decreased left ventricle (LV) function caused by genetic mutations or injury often leads to debilitating and fatal cardiovascular disease. LV cardiomyocytes are, therefore, a potentially valuable therapeutical target. Human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) are neither homogene...

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Detalles Bibliográficos
Autores principales:	Dark, Nicola, Cosson, Marie-Victoire, Tsansizi, Lorenza I., Owen, Thomas J., Ferraro, Elisa, Francis, Alice J., Tsai, Selina, Bouissou, Camille, Weston, Anne, Collinson, Lucy, Abi-Gerges, Najah, Miller, Paul E., MacLeod, Kenneth T., Ehler, Elisabeth, Mitter, Richard, Harding, Sian E., Smith, James C., Bernardo, Andreia S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163040/ https://www.ncbi.nlm.nih.gov/pubmed/37159667 http://dx.doi.org/10.1016/j.crmeth.2023.100456

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