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Double DAP-seq uncovered synergistic DNA binding of interacting bZIP transcription factors

Many eukaryotic transcription factors (TF) form homodimer or heterodimer complexes to regulate gene expression. Dimerization of BASIC LEUCINE ZIPPER (bZIP) TFs are critical for their functions, but the molecular mechanism underlying the DNA binding and functional specificity of homo- versus heterodi...

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Detalles Bibliográficos
Autores principales: Li, Miaomiao, Yao, Tao, Lin, Wanru, Hinckley, Will E., Galli, Mary, Muchero, Wellington, Gallavotti, Andrea, Chen, Jin-Gui, Huang, Shao-shan Carol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163045/
https://www.ncbi.nlm.nih.gov/pubmed/37147307
http://dx.doi.org/10.1038/s41467-023-38096-2