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Integrated glycomics and genetics analyses reveal a potential role for N-glycosylation of plasma proteins and IgGs, as well as the complement system, in the development of type 1 diabetes

AIMS/HYPOTHESIS: We previously demonstrated that N-glycosylation of plasma proteins and IgGs is different in children with recent-onset type 1 diabetes compared with their healthy siblings. To search for genetic variants contributing to these changes, we undertook a genetic association study of the...

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Detalles Bibliográficos
Autores principales: Rudman, Najda, Kaur, Simranjeet, Simunović, Vesna, Kifer, Domagoj, Šoić, Dinko, Keser, Toma, Štambuk, Tamara, Klarić, Lucija, Pociot, Flemming, Morahan, Grant, Gornik, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163086/
https://www.ncbi.nlm.nih.gov/pubmed/36907892
http://dx.doi.org/10.1007/s00125-023-05881-z