Melatonin inhibits senescence-associated melanin pigmentation through the p53-TYR pathway in human primary melanocytes and the skin of C57BL/6 J mice after UVB irradiation

ABSTRACT: UVB exposure accelerates skin aging and pigmentation. Melatonin effectively regulates tyrosinase (TYR) activity and aging. The purpose of this study was to determine the association between premature senescence and pigmentation, and the mechanism of melanin synthesis effected by melatonin....

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Detalles Bibliográficos
Autores principales: Ma, Li-Ping, Liu, Meng-Meng, Liu, Fang, Sun, Bo, Wang, Si-Nian, Chen, Jie, Yu, Hui-Jie, Yan, Juan, Tian, Mei, Gao, Ling, Liu, Qing-Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163137/
https://www.ncbi.nlm.nih.gov/pubmed/37032347
http://dx.doi.org/10.1007/s00109-023-02301-y

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