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Methylation of histone H3 lysine 4 is required for maintenance of beta cell function in adult mice

AIMS/HYPOTHESIS: Beta cells control glucose homeostasis via regulated production and secretion of insulin. This function arises from a highly specialised gene expression programme that is established during development and then sustained, with limited flexibility, in terminally differentiated cells....

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Detalles Bibliográficos
Autores principales: Vanderkruk, Ben, Maeshima, Nina, Pasula, Daniel J., An, Meilin, McDonald, Cassandra L., Suresh, Priya, Luciani, Dan S., Lynn, Francis C., Hoffman, Brad G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163146/
https://www.ncbi.nlm.nih.gov/pubmed/36912927
http://dx.doi.org/10.1007/s00125-023-05896-6

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