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Methylation of histone H3 lysine 4 is required for maintenance of beta cell function in adult mice
AIMS/HYPOTHESIS: Beta cells control glucose homeostasis via regulated production and secretion of insulin. This function arises from a highly specialised gene expression programme that is established during development and then sustained, with limited flexibility, in terminally differentiated cells....
Autores principales: | Vanderkruk, Ben, Maeshima, Nina, Pasula, Daniel J., An, Meilin, McDonald, Cassandra L., Suresh, Priya, Luciani, Dan S., Lynn, Francis C., Hoffman, Brad G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163146/ https://www.ncbi.nlm.nih.gov/pubmed/36912927 http://dx.doi.org/10.1007/s00125-023-05896-6 |
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