Cargando…

Natural history and treatment efficacy in an ambispective case series of NTRK-rearranged mesenchymal tumors

BACKGROUND: Apart for infantile fibrosarcoma (IFS), very little is known about NTRK-rearranged mesenchymal tumors (NMTs). The objective of this study is to describe the distribution, characteristics, natural history, and prognosis of NMT. PATIENTS AND METHODS: This study was carried out as a transla...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dufresne, A., Pissaloux, D., Ngo, C., Penel, N., Le Cesne, A., Macagno, N., Vanacker, H., Hénon, C., Jean-Denis, M., Rughoo, K., Tirode, F., Blay, J.-Y., Brahmi, M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163158/ https://www.ncbi.nlm.nih.gov/pubmed/37054503 http://dx.doi.org/10.1016/j.esmoop.2023.101202

Ejemplares similares

Molecular Classification of Endometrial Stromal Sarcomas Using RNA Sequencing Defines Nosological and Prognostic Subgroups with Different Natural History
por: Brahmi, Mehdi, et al.
Publicado: (2020)

Expanding the molecular spectrum of tenosynovial giant cell tumors
por: Gauduchon, Thibault, et al.
Publicado: (2022)

Outcome of 449 adult patients with rhabdomyosarcoma: an observational ambispective nationwide study
por: Bompas, Emmanuelle, et al.
Publicado: (2018)

Immunotherapy for Soft Tissue Sarcomas: Anti-PD1/PDL1 and Beyond
por: Fazel, Mina, et al.
Publicado: (2023)

Imaging findings of NTRK‑rearranged spindle cell neoplasms: A case series
por: Kobayashi, Hiroshi, et al.
Publicado: (2023)

Fusion partners of NTRK3 affect subcellular localization of the fusion kinase and cytomorphology of melanocytes
por: de la Fouchardière, Arnaud, et al.
Publicado: (2020)

French Sarcoma Group proposals for management of sarcoma patients during the COVID-19 outbreak
por: Penel, N., et al.
Publicado: (2020)

Therapeutic relevance of molecular screening program in patients with metastatic sarcoma: Analysis from the ProfiLER 01 trial
por: Arnaud-Coffin, Patrick, et al.
Publicado: (2020)

Very long‐term survivors among patients with metastatic soft tissue sarcoma
por: Carbonnaux, Mélodie, et al.
Publicado: (2019)

Broadening the spectrum of NTRK rearranged mesenchymal tumors and usefulness of pan-TRK immunohistochemistry for identification of NTRK fusions
por: Brčić, Iva, et al.
Publicado: (2020)

Oncogenic and drug sensitive NTRK1 rearrangements in lung cancer
por: Vaishnavi, A., et al.
Publicado: (2013)

Expression and prognostic significance of PDGF ligands and receptors across soft tissue sarcomas
por: Brahmi, M., et al.
Publicado: (2021)

Patterns of care and outcome of CIC‐rearranged sarcoma patients: A nationwide study of the French sarcoma group
por: Brahmi, Mehdi, et al.
Publicado: (2022)

Tocilizumab for the treatment of paraneoplastic inflammatory syndrome associated with angiomatoid fibrous histiocytoma
por: Eberst, Lauriane, et al.
Publicado: (2020)

Options thérapeutiques de prise en charge des sarcomes durant la pandémie COVID-19 : propositions du groupe sarcome français
por: Penel, Nicolas, et al.
Publicado: (2020)

TMP3-NTRK1 rearranged uterine sarcoma: A case report
por: Boyle, William, et al.
Publicado: (2020)

HGG-24. NTRK-rearranged infantile gliomas of suprasellar/ optic pathway origin
por: Lazow, Margot A, et al.
Publicado: (2022)

Evolution of Patterns of Care and Outcomes in the Real-Life Setting for Patients with Metastatic GIST Treated in Three French Expert Centers over Three Decades
por: Toulmonde, Maud, et al.
Publicado: (2023)

Impact of KIT exon 10 M541L allelic variant on the response to imatinib in aggressive fibromatosis: analysis of the desminib series by competitive allele specific Taqman PCR technology
por: Dufresne, Armelle, et al.
Publicado: (2014)

Durable Clinical Response to Entrectinib in NTRK1-Rearranged Non-Small Cell Lung Cancer
por: Farago, Anna F., et al.
Publicado: (2015)

Larotrectinib in a NTRK‐rearranged soft tissue sarcoma in the neoadjuvant setting: A case report
por: Percy, Catherine, et al.
Publicado: (2021)

Limited Accuracy of Pan-Trk Immunohistochemistry Screening for NTRK Rearrangements in Follicular-Derived Thyroid Carcinoma
por: Macerola, Elisabetta, et al.
Publicado: (2022)

A functional sgRNA-CRISPR screening method for generating murine RET and NTRK1 rearranged oncogenes
por: Schubert, Laura, et al.
Publicado: (2023)

Search for NTRK1 proto-oncogene rearrangements in human thyroid tumours originated after therapeutic radiation
por: Bounacer, A, et al.
Publicado: (2000)

Identification and characterization of a novel SCYL3-NTRK1 rearrangement in a colorectal cancer patient
por: Milione, Massimo, et al.
Publicado: (2017)

Non-small-cell lung cancer: how to manage ALK-, ROS1- and NTRK-rearranged disease
por: Marinelli, Daniele, et al.
Publicado: (2022)

NTRK‐rearranged spindle cell neoplasms are ubiquitous tumours of myofibroblastic lineage with a distinct methylation class
por: Tauziède‐Espariat, Arnault, et al.
Publicado: (2022)

Extensive gene rearrangements in the mitogenomes of congeneric annelid species and insights on the evolutionary history of the genus Ophryotrocha
por: Tempestini, Astrid, et al.
Publicado: (2020)

Intra‐ and extra‐cranial BCOR‐ITD tumours are separate entities within the BCOR ‐rearranged family
por: Bouchoucha, Yassine, et al.
Publicado: (2022)

Identification of biological factors predictive of response to imatinib mesylate in aggressive fibromatosis
por: Dufresne, A, et al.
Publicado: (2010)

NTRK Fusions in a Sarcomas Series: Pathology, Molecular and Clinical Aspects
por: Siozopoulou, Vasiliki, et al.
Publicado: (2022)

COVID-19 in Children with West Syndrome: An Ambispective Study
por: Madaan, Priyanka, et al.
Publicado: (2022)

NTRK rearranged sarcoma of the bone. Role for larotrectinib in the neoadjuvant setting of an ultra-rare tumor: a case report
por: Palmerini, Emanuela, et al.
Publicado: (2023)

ETMR-03. Intra- and extra-cranial BCOR-ITD tumours are separate entities within the BCOR-rearranged family
por: Bouchoucha, Yassine, et al.
Publicado: (2022)

Expression of the neurotrophic tyrosine kinase receptors, ntrk1 and ntrk2a, precedes expression of other ntrk genes in embryonic zebrafish
por: Hahn, Katie, et al.
Publicado: (2020)

NTRK1 rearrangement in colorectal cancer patients: evidence for actionable target using patient-derived tumor cell line
por: Lee, Su Jin, et al.
Publicado: (2015)

A rare case of recurrent ovarian cancer with TPM3-NTRK1 gene rearrangement: A case report
por: Endo, Yuta, et al.
Publicado: (2022)

Inhibition of EGFR and MEK surmounts entrectinib resistance in a brain metastasis model of NTRK1‐rearranged tumor cells
por: Suzuki, Chiaki, et al.
Publicado: (2022)

NTRK rearrangements in a subset of NF1-related malignant peripheral nerve sheath tumors as novel actionable target
por: Hiemcke-Jiwa, L. S., et al.
Publicado: (2022)

Conservative surgical treatment with fertility preservation in a young adult with NTRK rearranged spindle cell neoplasm of the uterine cervix
por: Bühler, Marco M., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_935rbe73ooqotiqkr9024nh3b2