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Major adverse cardiac events and cardiovascular toxicity with PARP inhibitors-based therapy for solid tumors: a systematic review and safety meta-analysis
BACKGROUND: Poly(ADP-ribose) polymerase (PARP) inhibitors (PARPi) provided significant antitumor activity in various tumors, mainly carrying deleterious mutations of BRCA1/BRCA2 genes. Only few data are available regarding the cardiac and vascular safety profile of this drug class. We carried out a...
Autores principales: | Palazzo, A., Ciccarese, C., Iacovelli, R., Cannizzaro, M.C., Stefani, A., Salvatore, L., Bria, E., Tortora, G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163166/ https://www.ncbi.nlm.nih.gov/pubmed/36893518 http://dx.doi.org/10.1016/j.esmoop.2023.101154 |
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